PURPOSE: To improve coronary vessel visualization in whole-heart coronary magnetic resonance angiography (CMRA), fat suppression is typically applied. However, recent studies have shown that cardiac fat can also have diagnostic value. To enhance CMRA image quality by improved fat suppression and to provide additionally fat-only information highly resolved, dual-echo Dixon CMRA approaches have been developed. METHODS: In this pilot study, approved by the institutional review board, 30 patients were investigated comparing whole-heart T1 -weighted dual-echo Dixon CMRA to conventional whole-heart fat-suppressed balanced fast field echo CMRA, integrated into a routine clinical protocol that includes the administration of gadolinium for perfusion and late enhancement measurements. Signal-to-noise-ratio, contrast-to-noise-ratio, and image quality were analyzed. RESULTS: Dual-echo Dixon significantly (P<0.000001) improved image quality compared with conventional fat-suppressed balanced fast field echo CMRA. Signal-to-noise-ratio and contrast-to-noise-ratio were found to be comparable when balanced fast field echo was performed before gadolinium and dual-echo Dixon fast field echo after gadolinium administration. CONCLUSION: Dual-echo Dixon can help to improve whole-heart CMRA image quality significantly. The additional whole-heart fat information delivered by this approach can support a number of new clinical studies addressing the diagnostic and the predictive value of intramyocardial and extramyocardial fatty deposits.
PURPOSE: To improve coronary vessel visualization in whole-heart coronary magnetic resonance angiography (CMRA), fat suppression is typically applied. However, recent studies have shown that cardiac fat can also have diagnostic value. To enhance CMRA image quality by improved fat suppression and to provide additionally fat-only information highly resolved, dual-echo Dixon CMRA approaches have been developed. METHODS: In this pilot study, approved by the institutional review board, 30 patients were investigated comparing whole-heart T1 -weighted dual-echo Dixon CMRA to conventional whole-heart fat-suppressed balanced fast field echo CMRA, integrated into a routine clinical protocol that includes the administration of gadolinium for perfusion and late enhancement measurements. Signal-to-noise-ratio, contrast-to-noise-ratio, and image quality were analyzed. RESULTS: Dual-echo Dixon significantly (P<0.000001) improved image quality compared with conventional fat-suppressed balanced fast field echo CMRA. Signal-to-noise-ratio and contrast-to-noise-ratio were found to be comparable when balanced fast field echo was performed before gadolinium and dual-echo Dixon fast field echo after gadolinium administration. CONCLUSION: Dual-echo Dixon can help to improve whole-heart CMRA image quality significantly. The additional whole-heart fat information delivered by this approach can support a number of new clinical studies addressing the diagnostic and the predictive value of intramyocardial and extramyocardial fatty deposits.
Authors: Rami Homsi; Michael Meier-Schroers; Jürgen Gieseke; Darius Dabir; Julian A Luetkens; Daniel L Kuetting; Claas P Naehle; Christian Marx; Hans H Schild; Daniel K Thomas; Alois M Sprinkart Journal: Int J Cardiovasc Imaging Date: 2015-09-30 Impact factor: 2.357
Authors: Mieke M P Driessen; Johannes M P J Breur; Ricardo P J Budde; Joep W M van Oorschot; Roland R J van Kimmenade; Gertjan Tj Sieswerda; Folkert J Meijboom; Tim Leiner Journal: Pediatr Radiol Date: 2015-01-01
Authors: Jon D Klingensmith; Addison L Elliott; Amy H Givan; Zechariah D Faszold; Cory L Mahan; Adam M Doedtman; Maria Fernandez-Del-Valle Journal: J Med Imaging (Bellingham) Date: 2019-02-07
Authors: Valentina Taviani; Diego Hernando; Christopher J Francois; Ann Shimakawa; Karl K Vigen; Scott K Nagle; Mark L Schiebler; Thomas M Grist; Scott B Reeder Journal: Magn Reson Med Date: 2013-11-01 Impact factor: 4.668
Authors: Alexander Isaak; Julian A Luetkens; Anton Faron; Christoph Endler; Narine Mesropyan; Christoph Katemann; Shuo Zhang; Patrick Kupczyk; Daniel Kuetting; Ulrike Attenberger; Darius Dabir Journal: J Cardiovasc Magn Reson Date: 2021-07-19 Impact factor: 5.364