Literature DB >> 23399470

Worming our way to Alzheimer's disease drug discovery.

Sangeetha Iyer1, Jonathan T Pierce-Shimomura.   

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Year:  2013        PMID： 23399470      PMCID： PMC4467874          DOI： 10.1016/j.biopsych.2012.12.026

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN： 0006-3223            Impact factor:   13.382


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  10 in total

Review 1.  Target-based drug discovery: is something wrong?

Authors:  Frank Sams-Dodd
Journal:  Drug Discov Today       Date:  2005-01-15       Impact factor: 7.851

2.  Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity.

Authors:  Allyson V McCormick; Jeanna M Wheeler; Chris R Guthrie; Nicole F Liachko; Brian C Kraemer
Journal:  Biol Psychiatry       Date:  2012-11-07       Impact factor: 13.382

3.  A small-molecule screen in C. elegans yields a new calcium channel antagonist.

Authors:  Trevor C Y Kwok; Nicole Ricker; Regina Fraser; Allen W Chan; Andrew Burns; Elise F Stanley; Peter McCourt; Sean R Cutler; Peter J Roy
Journal:  Nature       Date:  2006-05-04       Impact factor: 49.962

4.  A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans.

Authors:  Andrew R Burns; Iain M Wallace; Jan Wildenhain; Mike Tyers; Guri Giaever; Gary D Bader; Corey Nislow; Sean R Cutler; Peter J Roy
Journal:  Nat Chem Biol       Date:  2010-05-30       Impact factor: 15.040

5.  ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.

Authors:  Paige E Cramer; John R Cirrito; Daniel W Wesson; C Y Daniel Lee; J Colleen Karlo; Adriana E Zinn; Brad T Casali; Jessica L Restivo; Whitney D Goebel; Michael J James; Kurt R Brunden; Donald A Wilson; Gary E Landreth
Journal:  Science       Date:  2012-02-09       Impact factor: 47.728

Review 6.  The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

Authors:  John Hardy; Dennis J Selkoe
Journal:  Science       Date:  2002-07-19       Impact factor: 47.728

Review 7.  Evidence that non-fibrillar tau causes pathology linked to neurodegeneration and behavioral impairments.

Authors:  Kurt R Brunden; John Q Trojanowski; Virginia M-Y Lee
Journal:  J Alzheimers Dis       Date:  2008-08       Impact factor: 4.472

8.  Alzheimer disease in the US population: prevalence estimates using the 2000 census.

Authors:  Liesi E Hebert; Paul A Scherr; Julia L Bienias; David A Bennett; Denis A Evans
Journal:  Arch Neurol       Date:  2003-08

9.  Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z.

Authors:  Sager J Gosai; Joon Hyeok Kwak; Cliff J Luke; Olivia S Long; Dale E King; Kevin J Kovatch; Paul A Johnston; Tong Ying Shun; John S Lazo; David H Perlmutter; Gary A Silverman; Stephen C Pak
Journal:  PLoS One       Date:  2010-11-12       Impact factor: 3.240

10.  Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection.

Authors:  Read Pukkila-Worley; Rhonda Feinbaum; Natalia V Kirienko; Jonah Larkins-Ford; Annie L Conery; Frederick M Ausubel
Journal:  PLoS Genet       Date:  2012-06-14       Impact factor: 5.917
  10 in total
  1 in total

Review 1.  Towards High-Throughput Chemobehavioural Phenomics in Neuropsychiatric Drug Discovery.

Authors:  Jason Henry; Donald Wlodkowic
Journal:  Mar Drugs       Date:  2019-06-06       Impact factor: 5.118
  1 in total

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