Literature DB >> 2339667

Spontaneous osteo-arthritis of the knee-joint in C57BL mice receiving chronic oral treatment with NSAID's or prednisone.

A Pataki1, H P Graf, E Witzemann.   

Abstract

In a statistically planned study based on quantitative radiography, treatment for 25-26 weeks with the 2 NSAIDs, diclofenac sodium, or indomethacin (both 0.5 and 1.5 mg/kg p.o. daily), or prednisone (6 mg/kg p.o.) had no influence on the progression of spontaneous osteo-arthritis of the knee-joint of the C57BL mouse, by comparison with placebo-treated controls.

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Year:  1990        PMID: 2339667     DOI: 10.1007/bf01966449

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  10 in total

1.  Degenerative joint disease of mice as modified by adrenocorticotrophic hormone (ACTH).

Authors:  M SILBERBERG; R SILBERBERG
Journal:  Exp Med Surg       Date:  1955

2.  Degenerative joint disease in mice bearing anterior hypophyseal, ovarian and adrenal grafts.

Authors:  M SILBERBERG; R SILBERBERG; M OPDYKE
Journal:  Endocrinology       Date:  1954-01       Impact factor: 4.736

3.  Quantitative radiographic diagnosis of osteo-arthritis of the knee-joint in the C57BL mouse.

Authors:  A Pataki; R Reife; E Witzemann; H P Graf; A Schweizer
Journal:  Agents Actions       Date:  1990-03

4.  A new model of osteoarthritis in rabbits. III. Evaluation of anti-osteoarthritic effects of selected drugs administered intraarticularly.

Authors:  M Butler; C Colombo; L Hickman; E O'Byrne; R Steele; B Steinetz; J Quintavalla; N Yokoyama
Journal:  Arthritis Rheum       Date:  1983-11

5.  Triamcinolone hexacetonide protects against fibrillation and osteophyte formation following chemically induced articular cartilage damage.

Authors:  J M Williams; K D Brandt
Journal:  Arthritis Rheum       Date:  1985-11

6.  Qualitative radiographic diagnosis of osteo-arthritis of the knee joint in the C57BL mouse.

Authors:  A Pataki; R Fries; K Ochsner; E Witzemann
Journal:  Agents Actions       Date:  1987-10

7.  [Preventive effect of tribenoside in spontaneous arthrosis of the mouse].

Authors:  G Wilhelmi
Journal:  Z Rheumatol       Date:  1977 Mar-Apr       Impact factor: 1.372

8.  [Animal experiment studies on the effect of intra-articular injections of antiphlogistic-antirheumatic agents on articular cartilage in vivo].

Authors:  D A Kalbhen; M Schauer; B Wentsche
Journal:  Z Rheumatol       Date:  1978 Nov-Dec       Impact factor: 1.372

9.  A new model of osteoarthritis in rabbits. II. Evaluation of anti-osteoarthritic effects of selected antirheumatic drugs administered systemically.

Authors:  C Colombo; M Butler; L Hickman; M Selwyn; J Chart; B Steinetz
Journal:  Arthritis Rheum       Date:  1983-09

10.  Cartilage degradation by neutral proteoglycanases in experimental osteoarthritis. Suppression by steroids.

Authors:  J P Pelletier; J Martel-Pelletier
Journal:  Arthritis Rheum       Date:  1985-12
  10 in total
  1 in total

1.  Quantitative radiographic diagnosis of osteo-arthritis of the knee-joint in the C57BL mouse.

Authors:  A Pataki; R Reife; E Witzemann; H P Graf; A Schweizer
Journal:  Agents Actions       Date:  1990-03
  1 in total

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