Literature DB >> 23393076

Tales of how great drugs were brought down by a flawed rationale--response.

Edina Komlodi-Pasztor, Dan L Sackett, Tito Fojo.   

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Year:  2013        PMID： 23393076     DOI： 10.1158/1078-0432.CCR-12-2058

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


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  4 in total

1.  Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel.

Authors:  Christina M Scribano; Jun Wan; Karla Esbona; John B Tucker; Amber Lasek; Amber S Zhou; Lauren M Zasadil; Ryan Molini; Jonathan Fitzgerald; Angela M Lager; Jennifer J Laffin; Kayla Correia-Staudt; Kari B Wisinski; Amye J Tevaarwerk; Ruth O'Regan; Stephanie M McGregor; Amy M Fowler; Richard J Chappell; Tim S Bugni; Mark E Burkard; Beth A Weaver
Journal:  Sci Transl Med       Date:  2021-09-08       Impact factor: 17.956

2.  Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells.

Authors:  Anisha Kothari; Walter N Hittelman; Timothy C Chambers
Journal:  Cancer Res       Date:  2016-05-06       Impact factor: 12.701

3.  Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways.

Authors:  Magdalena Delgado; Randall R Rainwater; Billie Heflin; Alicja Urbaniak; Kaitlynn Butler; Mari Davidson; Reine M Protacio; Giulia Baldini; Andrea Edwards; Megan R Reed; Kevin D Raney; Timothy C Chambers
Journal:  J Biol Chem       Date:  2022-04-15       Impact factor: 5.486

4.  Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.

Authors:  Alejandro Peña; Aaron Sweeney; Alexander D Cook; Julia Locke; Maya Topf; Carolyn A Moores
Journal:  Structure       Date:  2020-02-20       Impact factor: 5.871
  4 in total

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