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Literature DB >> 23392843

Calreticulin and cancer.

Mohammadreza Zamanian¹, Abhi Veerakumarasivam, Syahril Abdullah, Rozita Rosli.

Abstract

Calreticulin (CRT) as a multi-functional endoplasmic reticulum protein is involved in a spectrum of cellular processes which ranges from calcium homeostasis and chaperoning to cell adhesion and finally malignant formation and progression. Previous studies have shown a contributing role for CRT in a range of different cancers. This present review will focus on the possible roles of CRT in the progression of malignant proliferation and the mechanisms involved in its contribution to cancer invasion.

Entities: Chemical Disease Gene

Mesh：

Substances：
Calreticulin

Year: 2013 PMID： 23392843 DOI： 10.1007/s12253-012-9600-2

Source DB: PubMed Journal: Pathol Oncol Res ISSN： 1219-4956 Impact factor: 3.201

79 in total

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Journal: Mod Pathol Date: 2010-09-10 Impact factor: 7.842

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Authors: M Michalak; E F Corbett; N Mesaeli; K Nakamura; M Opas
Journal: Biochem J Date: 1999-12-01 Impact factor: 3.857

5. Calreticulin is transcriptionally upregulated by heat shock, calcium and heavy metals.

Authors: T O Nguyen; J D Capra; R D Sontheimer
Journal: Mol Immunol Date: 1996 Mar-Apr Impact factor: 4.407

6. The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin.

Authors: Silvia Goicoechea; Manuel Antonio Pallero; Paul Eggleton; Marek Michalak; Joanne E Murphy-Ullrich
Journal: J Biol Chem Date: 2002-07-29 Impact factor: 5.157

7. An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer.

Authors: Su-Hyung Hong; David E Misek; Hong Wang; Eric Puravs; Thomas J Giordano; Joel K Greenson; Dean E Brenner; Diane M Simeone; Craig D Logsdon; Samir M Hanash
Journal: Cancer Res Date: 2004-08-01 Impact factor: 12.701

8. KCa2.3 channel-dependent hyperpolarization increases melanoma cell motility.

Authors: Aurelie Chantome; Alban Girault; Marie Potier; Christine Collin; Pascal Vaudin; Jean-Christophe Pagès; Christophe Vandier; Virginie Joulin
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9. Thrombospondin signaling through the calreticulin/LDL receptor-related protein co-complex stimulates random and directed cell migration.

Authors: A Wayne Orr; Carrie A Elzie; Dennis F Kucik; Joanne E Murphy-Ullrich
Journal: J Cell Sci Date: 2003-07-15 Impact factor: 5.285

10. Inhibition of nuclear hormone receptor activity by calreticulin.

Authors: S Dedhar; P S Rennie; M Shago; C Y Hagesteijn; H Yang; J Filmus; R G Hawley; N Bruchovsky; H Cheng; R J Matusik
Journal: Nature Date: 1994-02-03 Impact factor: 49.962

32 in total

1. Dissecting physical structure of calreticulin, an intrinsically disordered Ca²⁺-buffering chaperone from endoplasmic reticulum.

Authors: Anna Rita Migliaccio; Vladimir N Uversky
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2. Bioinformatic analyses of CALR mutations in myeloproliferative neoplasms support a role in signaling.

Authors: L Eder-Azanza; D Navarro; P Aranaz; F J Novo; N C P Cross; J L Vizmanos
Journal: Leukemia Date: 2014-06-12 Impact factor: 11.528

3. Structural Analysis of Calreticulin, an Endoplasmic Reticulum-Resident Molecular Chaperone.

Authors: Gunnar Houen; Peter Højrup; Evaldas Ciplys; Christine Gaboriaud; Rimantas Slibinskas
Journal: Prog Mol Subcell Biol Date: 2021

4. Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transition.

Authors: Shing-Hwa Liu; Wen-Jane Lee; De-Wei Lai; Sheng-Mao Wu; Chia-Yu Liu; Hsing-Ru Tien; Chien-Shan Chiu; Yen-Chun Peng; Yee-Jee Jan; Te-Hsin Chao; Hung-Chuan Pan; Meei-Ling Sheu
Journal: Mol Oncol Date: 2015-01-06 Impact factor: 6.603

5. Calreticulin nuclear translocalization alleviates CaM/CaMKII/CREB signaling pathway to enhance chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells.

Authors: Yi-Sheng Liu; Yu-Chun Chang; Wei-Wen Kuo; Ming-Cheng Chen; Tso-Fu Wang; Tung-Sheng Chen; Yueh-Min Lin; Chi-Cheng Li; Po-Hsiang Liao; Chih-Yang Huang
Journal: Aging (Albany NY) Date: 2022-06-20 Impact factor: 5.955

10. Calreticulin down-regulation inhibits the cell growth, invasion and cell cycle progression of human hepatocellular carcinoma cells.

Authors: Ruo Feng; Jianwen Ye; Chuang Zhou; Lei Qi; Zhe Fu; Bing Yan; Zhiwei Liang; Renfeng Li; Wenlong Zhai
Journal: Diagn Pathol Date: 2015-08-27 Impact factor: 2.644