Literature DB >> 23392286

Cost-effective and rapid blood analysis on a cell-phone.

Hongying Zhu1, Ikbal Sencan, Justin Wong, Stoyan Dimitrov, Derek Tseng, Keita Nagashima, Aydogan Ozcan.   

Abstract

We demonstrate a compact and cost-effective imaging cytometry platform installed on a cell-phone for the measurement of the density of red and white blood cells as well as hemoglobin concentration in human blood samples. Fluorescent and bright-field images of blood samples are captured using separate optical attachments to the cell-phone and are rapidly processed through a custom-developed smart application running on the phone for counting of blood cells and determining hemoglobin density. We evaluated the performance of this cell-phone based blood analysis platform using anonymous human blood samples and achieved comparable results to a standard bench-top hematology analyser. Test results can either be stored on the cell-phone memory or be transmitted to a central server, providing remote diagnosis opportunities even in field settings.

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Year:  2013        PMID: 23392286      PMCID: PMC3594636          DOI: 10.1039/c3lc41408f

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  14 in total

1.  Integrated rapid-diagnostic-test reader platform on a cellphone.

Authors:  Onur Mudanyali; Stoyan Dimitrov; Uzair Sikora; Swati Padmanabhan; Isa Navruz; Aydogan Ozcan
Journal:  Lab Chip       Date:  2012-05-17       Impact factor: 6.799

2.  Ultra wide-field lens-free monitoring of cells on-chip.

Authors:  Aydogan Ozcan; Utkan Demirci
Journal:  Lab Chip       Date:  2007-11-01       Impact factor: 6.799

3.  Low cost, portable detection of gold nanoparticle-labeled microfluidic immunoassay with camera cell phone.

Authors:  Yao Lu; Weiwei Shi; Jianhua Qin; Bingcheng Lin
Journal:  Electrophoresis       Date:  2009-02       Impact factor: 3.535

4.  Surface plasmon resonance chemical sensing on cell phones.

Authors:  Pakorn Preechaburana; Marcos Collado Gonzalez; Anke Suska; Daniel Filippini
Journal:  Angew Chem Int Ed Engl       Date:  2012-10-16       Impact factor: 15.336

5.  Point-of-care colorimetric detection with a smartphone.

Authors:  Li Shen; Joshua A Hagen; Ian Papautsky
Journal:  Lab Chip       Date:  2012-11-07       Impact factor: 6.799

6.  Cell-phone-based measurement of TSH using Mie scatter optimized lateral flow assays.

Authors:  David J You; Tu San Park; Jeong-Yeol Yoon
Journal:  Biosens Bioelectron       Date:  2012-07-20       Impact factor: 10.618

7.  Lensfree microscopy on a cellphone.

Authors:  Derek Tseng; Onur Mudanyali; Cetin Oztoprak; Serhan O Isikman; Ikbal Sencan; Oguzhan Yaglidere; Aydogan Ozcan
Journal:  Lab Chip       Date:  2010-05-06       Impact factor: 6.799

8.  Quantum dot enabled detection of Escherichia coli using a cell-phone.

Authors:  Hongying Zhu; Uzair Sikora; Aydogan Ozcan
Journal:  Analyst       Date:  2012-03-07       Impact factor: 4.616

9.  A personalized food allergen testing platform on a cellphone.

Authors:  Ahmet F Coskun; Justin Wong; Delaram Khodadadi; Richie Nagi; Andrew Tey; Aydogan Ozcan
Journal:  Lab Chip       Date:  2013-02-21       Impact factor: 6.799

10.  Mobile phone based clinical microscopy for global health applications.

Authors:  David N Breslauer; Robi N Maamari; Neil A Switz; Wilbur A Lam; Daniel A Fletcher
Journal:  PLoS One       Date:  2009-07-22       Impact factor: 3.240

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  54 in total

1.  Albumin testing in urine using a smart-phone.

Authors:  Ahmet F Coskun; Richie Nagi; Kayvon Sadeghi; Stephen Phillips; Aydogan Ozcan
Journal:  Lab Chip       Date:  2013-11-07       Impact factor: 6.799

2.  Quantification of plant chlorophyll content using Google Glass.

Authors:  Bingen Cortazar; Hatice Ceylan Koydemir; Derek Tseng; Steve Feng; Aydogan Ozcan
Journal:  Lab Chip       Date:  2015-02-11       Impact factor: 6.799

3.  Evaluation of a Mobile Phone-Based Microscope for Screening of Schistosoma haematobium Infection in Rural Ghana.

Authors:  Isaac I Bogoch; Hatice C Koydemir; Derek Tseng; Richard K D Ephraim; Evans Duah; Joseph Tee; Jason R Andrews; Aydogan Ozcan
Journal:  Am J Trop Med Hyg       Date:  2017-06       Impact factor: 2.345

4.  Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array.

Authors:  Isa Navruz; Ahmet F Coskun; Justin Wong; Saqib Mohammad; Derek Tseng; Richie Nagi; Stephen Phillips; Aydogan Ozcan
Journal:  Lab Chip       Date:  2013-08-12       Impact factor: 6.799

5.  A smart preparation strategy for point-of-care cellular counting of trace volumes of human blood.

Authors:  Xinyi Li; Qiong Deng; Hongping Liu; Youwang Lei; Pengwei Fan; Bin Wang; Yangfei Chen; Zachary J Smith; Yuchen Tang; Tingjuan Gao
Journal:  Anal Bioanal Chem       Date:  2019-04-11       Impact factor: 4.142

6.  A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering.

Authors:  Uihan Kim; Jaewoo Song; Suho Ryu; Soocheol Kim; Chulmin Joo
Journal:  J Vis Exp       Date:  2016-12-07       Impact factor: 1.355

7.  Fluorescent imaging of single nanoparticles and viruses on a smart phone.

Authors:  Qingshan Wei; Hangfei Qi; Wei Luo; Derek Tseng; So Jung Ki; Zhe Wan; Zoltán Göröcs; Laurent A Bentolila; Ting-Ting Wu; Ren Sun; Aydogan Ozcan
Journal:  ACS Nano       Date:  2013-09-12       Impact factor: 15.881

8.  Multimode smartphone biosensing: the transmission, reflection, and intensity spectral (TRI)-analyzer.

Authors:  Kenneth D Long; Elizabeth V Woodburn; Huy M Le; Utsav K Shah; Steven S Lumetta; Brian T Cunningham
Journal:  Lab Chip       Date:  2017-09-26       Impact factor: 6.799

Review 9.  Cellphone-based devices for bioanalytical sciences.

Authors:  Sandeep Kumar Vashist; Onur Mudanyali; E Marion Schneider; Roland Zengerle; Aydogan Ozcan
Journal:  Anal Bioanal Chem       Date:  2013-11-28       Impact factor: 4.142

Review 10.  Biomedical imaging and sensing using flatbed scanners.

Authors:  Zoltán Göröcs; Aydogan Ozcan
Journal:  Lab Chip       Date:  2014-09-07       Impact factor: 6.799

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