Literature DB >> 23374871

Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus.

Mebarek Bahnous1, Abdelmalek Bouraiou, Meryem Chelghoum, Sofiane Bouacida, Thierry Roisnel, Farida Smati, Chafia Bentchouala, Philippe C Gros, Ali Belfaitah.   

Abstract

Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23374871     DOI: 10.1016/j.bmcl.2013.01.004

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  4 in total

Review 1.  Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950-2021 Comprehensive Overview.

Authors:  Ria Gupta; Sumit Sharma; Rohit Singh; Ram A Vishwakarma; Serge Mignani; Parvinder Pal Singh
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-30

2.  Crystal structure of 1-[2-(4-chloro-phen-yl)-4,5-diphenyl-1H-imidazol-1-yl]propan-2-ol.

Authors:  Shaaban K Mohamed; Adel A Marzouk; Mustafa R Albayati; Antar A Abdelhamid; Jim Simpson
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2017-01-01

3.  Antifungal Activity of 1,4-Dialkoxynaphthalen-2-Acyl Imidazolium Salts by Inducing Apoptosis of Pathogenic Candida spp.

Authors:  Jisue Lee; Jae-Goo Kim; Haena Lee; Tae Hoon Lee; Ki-Young Kim; Hakwon Kim
Journal:  Pharmaceutics       Date:  2021-02-27       Impact factor: 6.321

4.  Crystal structure of ethyl 2-[2-(4-methyl-benzo-yl)-5-p-tolyl-1H-imidazol-1-yl]acetate.

Authors:  E Arockia Jeya Yasmi Prabha; S Suresh Kumar; Anil K Padala; Qazi Naveed Ahmed; S Athimoolam
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2016-02-17
  4 in total

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