Sensitivity of joint moments to changes in walking speed and body-weight-support are interdependent and vary across joints.

We investigated the effect of simultaneous changes in body-weight-support level and walking speed on mean peak internal joint moments at the ankle, knee and hip. We hypothesized that observed changes in these joint moments would be approximately linear with both body-weight-support and walking speed and would be similar across joints. Kinematic and kinetic data were collected from 8 unimpaired adult subjects walking on an instrumented treadmill while wearing a dynamically controlled overhead support harness. Subjects walked with four levels of body-weight-support (0%, 20%, 40%, and 60% of bodyweight) at three walking speeds (0.4, 0.6, and 0.8 statures/s, ranging on average from 0.7 to 1.4m/s). Data were used to calculate mean peak joint moments across subjects for each condition. In general, subjects' mean peak joint moments decreased linearly with decreasing walking speed and with increasing body-weight-support, except the knee extension moment, which showed a quadratic relationship with walking speed and no significant change with body-weight-support. All joint moments, with the exception of knee extension, showed a significant interaction effect between walking speed and body-weight-support, indicating that the sensitivity of these joint moments to changes in these variables was interdependent. In most cases, the ankle and hip extension moments showed the largest sensitivity to walking speed. The ankle moment was observed to have the greatest sensitivity to body-weight-support. This finding, that altering walking speed and body-weight-support level results in non-uniform changes in peak moments across joints, suggests that further research is warranted to establish the set of combined speed and support conditions that produce motor patterns supportive of normal gait retraining.