Literature DB >> 23370418

The journey to femtosecond laser-assisted cataract surgery: new beginnings or a false dawn?

S Trikha1, A M J Turnbull, R J Morris, D F Anderson, P Hossain.   

Abstract

Femtosecond laser-assisted cataract surgery (FLACS) represents a potential paradigm shift in cataract surgery, but it is not without controversy. Advocates of the technology herald FLACS as a revolution that promises superior outcomes and an improved safety profile for patients. Conversely, detractors point to the large financial costs involved and claim that similar results are achievable with conventional small-incision phacoemulsification. This review provides a balanced and comprehensive account of the development of FLACS since its inception. It explains the physiology and mechanics underlying the technology, and critically reviews the outcomes and implications of initial studies. The benefits and limitations of using femtosecond laser accuracy to create corneal incisions, anterior capsulotomy, and lens fragmentation are explored, with reference to the main platforms, which currently offer FLACS. Economic considerations are discussed, in addition to the practicalities associated with the implementation of FLACS in a healthcare setting. The influence on surgical training and skills is considered and possible future applications of the technology introduced. While in its infancy, FLACS sets out the exciting possibility of a new level of precision in cataract surgery. However, further work in the form of large scale, phase 3 randomised controlled trials are required to demonstrate whether its theoretical benefits are significant in practice and worthy of the necessary huge financial investment and system overhaul. Whether it gains widespread acceptance is likely to be influenced by a complex interplay of scientific and socio-economic factors in years to come.

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Mesh:

Year:  2013        PMID: 23370418      PMCID: PMC3625999          DOI: 10.1038/eye.2012.293

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  64 in total

1.  Porcine model to compare real-time intraocular pressure during LASIK with a mechanical microkeratome and femtosecond laser.

Authors:  José L Hernández-Verdejo; Miguel A Teus; José M Román; Gema Bolívar
Journal:  Invest Ophthalmol Vis Sci       Date:  2007-01       Impact factor: 4.799

2.  Benchmark standards for refractive outcomes after NHS cataract surgery.

Authors:  R P Gale; M Saldana; R L Johnston; B Zuberbuhler; M McKibbin
Journal:  Eye (Lond)       Date:  2007-08-24       Impact factor: 3.775

3.  Tilt and decentration of spherical and aspheric intraocular lenses: effect on higher-order aberrations.

Authors:  Martin Baumeister; Jens Bühren; Thomas Kohnen
Journal:  J Cataract Refract Surg       Date:  2009-06       Impact factor: 3.351

4.  Cataract surgery complication rates.

Authors:  Luciano P Bellini; Graciela S Brum; Rafael S Grossi; Claudia Borowsky
Journal:  Ophthalmology       Date:  2008-08       Impact factor: 12.079

Review 5.  Femtosecond lasers in ophthalmology.

Authors:  H Kaz Soong; João Baptista Malta
Journal:  Am J Ophthalmol       Date:  2008-10-18       Impact factor: 5.258

6.  Initial clinical evaluation of an intraocular femtosecond laser in cataract surgery.

Authors:  Zoltan Nagy; Agnes Takacs; Tamas Filkorn; Melvin Sarayba
Journal:  J Refract Surg       Date:  2009-12       Impact factor: 3.573

7.  Non-invasive bleaching of the human lens by femtosecond laser photolysis.

Authors:  Line Kessel; Lars Eskildsen; Mike van der Poel; Michael Larsen
Journal:  PLoS One       Date:  2010-03-16       Impact factor: 3.240

8.  The Cataract National Dataset electronic multi-centre audit of 55,567 operations: updating benchmark standards of care in the United Kingdom and internationally.

Authors:  P Jaycock; R L Johnston; H Taylor; M Adams; D M Tole; P Galloway; C Canning; J M Sparrow
Journal:  Eye (Lond)       Date:  2007-11-23       Impact factor: 3.775

9.  The effect of phacoemulsification energy on the redox state of cultured human corneal endothelial cells.

Authors:  Young Joo Shin; Yutaro Nishi; Christoph Engler; Joann Kang; Sarah Hashmi; Albert S Jun; Peter L Gehlbach; Roy S Chuck
Journal:  Arch Ophthalmol       Date:  2009-04

Review 10.  Femtosecond laser in laser in situ keratomileusis.

Authors:  Marcella Q Salomão; Steven E Wilson
Journal:  J Cataract Refract Surg       Date:  2010-06       Impact factor: 3.351

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  21 in total

1.  Investigating the ocular temperature rise during femtosecond laser lens fragmentation: an in vitro study.

Authors:  Rita Mencucci; Sara Matteoli; Andrea Corvi; Luca Terracciano; Eleonora Favuzza; Stefano Gherardini; Filippo Caruso; Roberto Bellucci
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-10-21       Impact factor: 3.117

2.  Femtosecond laser capsulotomy versus manual capsulotomy: a Meta-analysis.

Authors:  Dao-Wei Qian; Hai-Ke Guo; Shang-Li Jin; Hong-Yang Zhang; Yuan-Cun Li
Journal:  Int J Ophthalmol       Date:  2016-03-18       Impact factor: 1.779

3.  Femtosecond laser-assisted cataract surgery compared with phacoemulsification: the FACT non-inferiority RCT.

Authors:  Alexander C Day; Jennifer M Burr; Kate Bennett; Rachael Hunter; Catey Bunce; Caroline J Doré; Mayank A Nanavaty; Kamaljit S Balaggan; Mark R Wilkins
Journal:  Health Technol Assess       Date:  2021-01       Impact factor: 4.014

Review 4.  Visual and refractive outcomes of laser cataract surgery.

Authors:  Heather Chen; Thomas Hyatt; Natalie Afshari
Journal:  Curr Opin Ophthalmol       Date:  2014-01       Impact factor: 3.761

5.  Comparison of intra-ocular pressure changes with liquid or flat applanation interfaces in a femtosecond laser platform.

Authors:  G P Williams; H P Ang; B L George; Y C Liu; G Peh; L Izquierdo; D T Tan; J S Mehta
Journal:  Sci Rep       Date:  2015-10-06       Impact factor: 4.379

Review 6.  A Comparison of Different Operating Systems for Femtosecond Lasers in Cataract Surgery.

Authors:  B M Wu; G P Williams; A Tan; J S Mehta
Journal:  J Ophthalmol       Date:  2015-09-21       Impact factor: 1.909

7.  Comparison of clinical outcomes, patient, and surgeon satisfaction following topical versus peribulbar anesthesia for phacoemulsification and intraocular lens implantation: a randomized, controlled trial.

Authors:  Kuldeep Dole; Sucheta Kulkarni; Kavita D Shisode; Rahul Deshpande; Nilesh Kakade; Rajiv Khandekar; Madan Deshpande
Journal:  Indian J Ophthalmol       Date:  2014-09       Impact factor: 1.848

8.  Intraocular Pressure Reduction after Femtolaser Assisted Cataract Surgery and Its Association with the Use of Ultrasound.

Authors:  Hana Abouzeid; Walter Ferrini; Murielle Bochud
Journal:  Medicina (Kaunas)       Date:  2021-05-01       Impact factor: 2.430

9.  The effects of a low-energy, high frequency liquid optic interface femtosecond laser system on lens capsulotomy.

Authors:  Geraint P Williams; Ben L George; Yoke R Wong; Xin-Yi Seah; Heng-Pei Ang; Mun Kitt A Loke; Shian Chao Tay; Jod S Mehta
Journal:  Sci Rep       Date:  2016-04-19       Impact factor: 4.379

10.  Randomised, single-masked non-inferiority trial of femtosecond laser-assisted versus manual phacoemulsification cataract surgery for adults with visually significant cataract: the FACT trial protocol.

Authors:  Alexander C Day; Jennifer M Burr; Catey Bunce; Caroline J Doré; Yvonne Sylvestre; Richard P L Wormald; Jeff Round; Victoria McCudden; Gary Rubin; Mark R Wilkins
Journal:  BMJ Open       Date:  2015-11-27       Impact factor: 2.692

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