Literature DB >> 23367084

Improved polyimide thin-film electrodes for neural implants.

Juan S Ordonez1, Christian Boehler, Martin Schuettler, Thomas Stieglitz.   

Abstract

Thin-film electrode arrays for neural implants are necessary when large integration densities of stimulating or recording channels are required. However, delamination of the metallic layers from the polymer substrate leads to early failure of the device. Based on new adhesion studies of polyimide to SiC and diamond-like carbon (DLC) the authors successfully fabricated a 232-channel electrode array for retinal stimulation with improved adhesion. Layers of SiC and DLC were integrated into the fabrication procedure of polyimide-platinum (Pt) arrays to create fully coated metal wires, which adhere to the polyimide substrate even after 1 year of accelerated aging in saline solution. Studies on the inter-diffusion of Pt and SiC were conducted to establish an optimal thickness for a gold core of the platinum tracks, which is used for reducing the electrical track resistance. Furthermore, the electrochemical behaviour of the stimulating contacts coated with IrOx were studied in a long-term pulse tests over millions of pulses showing no deterioration of the coating.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 23367084     DOI: 10.1109/EMBC.2012.6347149

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN: 1557-170X


  11 in total

1.  The Materials Science Foundation Supporting the Microfabrication of Reliable Polyimide-Metal Neuroelectronic Interfaces.

Authors:  Cary A Kuliasha; Jack W Judy
Journal:  Adv Mater Technol       Date:  2021-05-03

2.  The development of neural stimulators: a review of preclinical safety and efficacy studies.

Authors:  Robert K Shepherd; Joel Villalobos; Owen Burns; David A X Nayagam
Journal:  J Neural Eng       Date:  2018-05-14       Impact factor: 5.379

3.  in vitro Reactive-Accelerated-Aging (RAA) Assessment of Tissue-Engineered Electronic Nerve Interfaces (TEENI).

Authors:  Cary A Kuliasha; Jack W Judy
Journal:  Annu Int Conf IEEE Eng Med Biol Soc       Date:  2018-07

4.  A Novel Lead Design for Modulation and Sensing of Deep Brain Structures.

Authors:  Allison T Connolly; Rio J Vetter; Jamille F Hetke; Benjamin A Teplitzky; Daryl R Kipke; David S Pellinen; David J Anderson; Kenneth B Baker; Jerrold L Vitek; Matthew D Johnson
Journal:  IEEE Trans Biomed Eng       Date:  2015-10-28       Impact factor: 4.538

5.  Microtopographical patterns promote different responses in fibroblasts and Schwann cells: A possible feature for neural implants.

Authors:  Sahba Mobini; Cary A Kuliasha; Zachary A Siders; Nicole A Bohmann; Syed-Mustafa Jamal; Jack W Judy; Christine E Schmidt; Anthony B Brennan
Journal:  J Biomed Mater Res A       Date:  2020-06-29       Impact factor: 4.396

6.  Concept and Development of an Electronic Framework Intended for Electrode and Surrounding Environment Characterization In Vivo.

Authors:  Stefan B Rieger; Jennifer Pfau; Thomas Stieglitz; Maria Asplund; Juan S Ordonez
Journal:  Sensors (Basel)       Date:  2016-12-30       Impact factor: 3.576

7.  High-Density μLED-Based Optical Cochlear Implant With Improved Thermomechanical Behavior.

Authors:  Eric Klein; Christian Gossler; Oliver Paul; Patrick Ruther
Journal:  Front Neurosci       Date:  2018-10-01       Impact factor: 4.677

8.  Quantitative synchrotron X-ray tomography of the material-tissue interface in rat cortex implanted with neural probes.

Authors:  Thomas Böhm; Kevin Joseph; Matthias Kirsch; Riko Moroni; André Hilger; Markus Osenberg; Ingo Manke; Midori Johnston; Thomas Stieglitz; Ulrich G Hofmann; Carola A Haas; Simon Thiele
Journal:  Sci Rep       Date:  2019-05-21       Impact factor: 4.379

9.  Numerical Evaluation on Residual Thermal Stress-Induced Delamination at PDMS-Metal Interface of Neural Prostheses.

Authors:  Yuyang Mao; Ivan Pechenizkiy; Thomas Stieglitz; Theodor Doll
Journal:  Micromachines (Basel)       Date:  2021-06-08       Impact factor: 2.891

Review 10.  Ultraflexible Neural Electrodes for Long-Lasting Intracortical Recording.

Authors:  Fei He; Roy Lycke; Mehran Ganji; Chong Xie; Lan Luan
Journal:  iScience       Date:  2020-07-20
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.