Literature DB >> 23362267

Bacterial small RNA-based negative regulation: Hfq and its accomplices.

Nicholas De Lay1, Daniel J Schu, Susan Gottesman.   

Abstract

A large group of bacterial small regulatory RNAs (sRNAs) use the Hfq chaperone to mediate pairing with and regulation of mRNAs. Recent findings help to clarify how Hfq acts and highlight the role of the endonuclease RNase E and its associated proteins (the degradosome) in negative regulation by these sRNAs. sRNAs frequently uncouple transcription and translation by blocking ribosome access to the mRNA, allowing other proteins access to the mRNA. As more examples of sRNA-mediated regulation are studied, more variations on how Hfq, RNase E, and other proteins collaborate to bring about sRNA-based regulation are being found.

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Year:  2013        PMID： 23362267      PMCID： PMC3605619          DOI： 10.1074/jbc.R112.441386

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  68 in total

1.  Predicted structure and phyletic distribution of the RNA-binding protein Hfq.

Authors:  Xueguang Sun; Igor Zhulin; Roger M Wartell
Journal:  Nucleic Acids Res       Date:  2002-09-01       Impact factor: 16.971

Review 2.  Multiple activities of RNA-binding proteins S1 and Hfq.

Authors:  Eliane Hajnsdorf; Irina V Boni
Journal:  Biochimie       Date:  2012-02-18       Impact factor: 4.079

3.  Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition.

Authors:  Evelyn Sauer; Steffen Schmidt; Oliver Weichenrieder
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-29       Impact factor: 11.205

Review 4.  The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.

Authors:  Marc R Fabian; Nahum Sonenberg
Journal:  Nat Struct Mol Biol       Date:  2012-06-05       Impact factor: 15.369

5.  Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.

Authors:  Maria A Schumacher; Robert F Pearson; Thorleif Møller; Poul Valentin-Hansen; Richard G Brennan
Journal:  EMBO J       Date:  2002-07-01       Impact factor: 11.598

6.  Identification of the Hfq-binding site on DsrA RNA: Hfq binds without altering DsrA secondary structure.

Authors:  Cristin C Brescia; Peter J Mikulecky; Andrew L Feig; Darren D Sledjeski
Journal:  RNA       Date:  2003-01       Impact factor: 4.942

7.  Genomic analysis in Escherichia coli demonstrates differential roles for polynucleotide phosphorylase and RNase II in mRNA abundance and decay.

Authors:  Bijoy K Mohanty; Sidney R Kushner
Journal:  Mol Microbiol       Date:  2003-10       Impact factor: 3.501

8.  The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria.

Authors:  Gene-Wei Li; Eugene Oh; Jonathan S Weissman
Journal:  Nature       Date:  2012-03-28       Impact factor: 49.962

9.  Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli.

Authors:  Eric Massé; Freddy E Escorcia; Susan Gottesman
Journal:  Genes Dev       Date:  2003-09-15       Impact factor: 12.890

10.  The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAs.

Authors:  Aixia Zhang; Karen M Wassarman; Joaquin Ortega; Alasdair C Steven; Gisela Storz
Journal:  Mol Cell       Date:  2002-01       Impact factor: 19.328
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  126 in total

Review 1.  The spectrum of activity of the small RNA DsrA: not so narrow after all.

Authors:  David Lalaouna; Eric Massé
Journal:  Curr Genet       Date:  2015-11-25       Impact factor: 3.886

2.  Hfqs in Bacillus anthracis: Role of protein sequence variation in the structure and function of proteins in the Hfq family.

Authors:  Catherine Vrentas; Rodolfo Ghirlando; Andrea Keefer; Zonglin Hu; Aurelie Tomczak; Apostolos G Gittis; Athulaprabha Murthi; David N Garboczi; Susan Gottesman; Stephen H Leppla
Journal:  Protein Sci       Date:  2015-08-30       Impact factor: 6.725

3.  A small RNA activates CFA synthase by isoform-specific mRNA stabilization.

Authors:  Kathrin Sophie Fröhlich; Kai Papenfort; Agnes Fekete; Jörg Vogel
Journal:  EMBO J       Date:  2013-10-18       Impact factor: 11.598

Review 4.  Target activation by regulatory RNAs in bacteria.

Authors:  Kai Papenfort; Carin K Vanderpool
Journal:  FEMS Microbiol Rev       Date:  2015-04-30       Impact factor: 16.408

5.  Two-level inhibition of galK expression by Spot 42: Degradation of mRNA mK2 and enhanced transcription termination before the galK gene.

Authors:  Xun Wang; Sang Chun Ji; Heung Jin Jeon; Yonho Lee; Heon M Lim
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-04       Impact factor: 11.205

Review 6.  Application of TALEs, CRISPR/Cas and sRNAs as trans-acting regulators in prokaryotes.

Authors:  Matthew F Copeland; Mark C Politz; Brian F Pfleger
Journal:  Curr Opin Biotechnol       Date:  2014-03-12       Impact factor: 9.740

Review 7.  RNA silencing in plant symbiotic bacteria: Insights from a protein-centric view.

Authors:  José I Jiménez-Zurdo; Marta Robledo
Journal:  RNA Biol       Date:  2017-09-13       Impact factor: 4.652

Review 8.  Small non-coding RNAs in plant-pathogenic Xanthomonas spp.

Authors:  Ulrike Abendroth; Cornelius Schmidtke; Ulla Bonas
Journal:  RNA Biol       Date:  2014-02-27       Impact factor: 4.652

9.  sRNA-Mediated Control of Transcription Termination in E. coli.

Authors:  Nadezda Sedlyarova; Ilya Shamovsky; Binod K Bharati; Vitaly Epshtein; Jiandong Chen; Susan Gottesman; Renée Schroeder; Evgeny Nudler
Journal:  Cell       Date:  2016-09-22       Impact factor: 41.582

10.  Transcription of the Subtilase Cytotoxin Gene subAB 1 in Shiga Toxin-Producing Escherichia coli Is Dependent on hfq and hns.

Authors:  Laura Heinisch; Katharina Zoric; Maike Krause; Herbert Schmidt
Journal:  Appl Environ Microbiol       Date:  2019-10-01       Impact factor: 4.792
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