| Literature DB >> 23345921 |
Abstract
The article explores the possibility that the ordering of bio-organic molecules into a homochiral assembly at the origin of life was performed not in aqueous solutions of amino acids or related materials but in racemic glyceraldehyde in the "formose" reaction at high concentration and temperature. Based on physical chemical evidence and computer simulations of condensed fluids, it is argued that the isomerization kinetics of glyceraldehyde is responszible of the symmetry break and the ordering of molecules into homochiral domains.Entities:
Keywords: formose reaction; homochirality; origin of life
Year: 2005 PMID: 23345921 PMCID: PMC3456342 DOI: 10.1007/s10867-005-6063-7
Source DB: PubMed Journal: J Biol Phys ISSN: 0092-0606 Impact factor: 1.365