Literature DB >> 23345684

Models of assembly and disassembly of individual microtubules: stochastic and averaged equations.

H Bolterauer1, H J Limbach, J A Tuszyński.   

Abstract

In this paper we present solutions of the master equations for the microtubule length and show that the local probability for rescues or catastrophes can lead to bell-shaped length histograms. Conversely, as already known, non-local probabilities for these events result in exponential length histograms. We also derive master equations for a stabilizing cap and obtain a new boundary condition which provides an explanation of the results obtained in dilution and cutting experiments.

Keywords:  Dynamic instability; Master equations; Microtubules

Year:  1999        PMID: 23345684      PMCID: PMC3456067          DOI: 10.1023/A:1005159215657

Source DB:  PubMed          Journal:  J Biol Phys        ISSN: 0092-0606            Impact factor:   1.365


  47 in total

1.  Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

Authors:  D N Drechsel; A A Hyman; M H Cobb; M W Kirschner
Journal:  Mol Biol Cell       Date:  1992-10       Impact factor: 4.138

2.  A chemical kinetics model for microtubule oscillations

Authors: 
Journal:  J Theor Biol       Date:  1999-03-07       Impact factor: 2.691

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Authors:  A Marx; A Jagla; E Mandelkow
Journal:  Eur Biophys J       Date:  1990       Impact factor: 1.733

4.  Monte Carlo study of the GTP cap in a five-start helix model of a microtubule.

Authors:  Y D Chen; T L Hill
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

5.  Dynamic instability of microtubule growth.

Authors:  T Mitchison; M Kirschner
Journal:  Nature       Date:  1984 Nov 15-21       Impact factor: 49.962

6.  Cold depolymerization of microtubules to double rings: geometric stabilization of assemblies.

Authors:  R Melki; M F Carlier; D Pantaloni; S N Timasheff
Journal:  Biochemistry       Date:  1989-11-14       Impact factor: 3.162

Review 7.  What makes microtubules dynamic?

Authors:  P M Bayley
Journal:  J Cell Sci       Date:  1990-03       Impact factor: 5.285

8.  Oscillations in microtubule polymerization: the rate of GTP regeneration on tubulin controls the period.

Authors:  R Melki; M F Carlier; D Pantaloni
Journal:  EMBO J       Date:  1988-09       Impact factor: 11.598

9.  An oscillatory mode for microtubule assembly.

Authors:  F Pirollet; D Job; R L Margolis; J R Garel
Journal:  EMBO J       Date:  1987-11       Impact factor: 11.598

10.  Dilution of individual microtubules observed in real time in vitro: evidence that cap size is small and independent of elongation rate.

Authors:  R A Walker; N K Pryer; E D Salmon
Journal:  J Cell Biol       Date:  1991-07       Impact factor: 10.539

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  6 in total

1.  Modeling the effects of drug binding on the dynamic instability of microtubules.

Authors:  Peter Hinow; Vahid Rezania; Manu Lopus; Mary Ann Jordan; Jack A Tuszyński
Journal:  Phys Biol       Date:  2011-08-12       Impact factor: 2.583

2.  Compartment volume influences microtubule dynamic instability: a model study.

Authors:  Albertas Janulevicius; Jaap van Pelt; Arjen van Ooyen
Journal:  Biophys J       Date:  2006-02-01       Impact factor: 4.033

3.  Microtubule assembly of isotypically purified tubulin and its mixtures.

Authors:  Vahid Rezania; Olga Azarenko; Mary Ann Jordan; Hannes Bolterauer; Richard F Ludueña; J Torin Huzil; Jack A Tuszynski
Journal:  Biophys J       Date:  2008-05-23       Impact factor: 4.033

4.  Microtubule Dynamics may Embody a Stationary Bipolarity Forming Mechanism Related to the Prokaryotic Division Site Mechanism (Pole-to-Pole Oscillations).

Authors:  A Hunding
Journal:  J Biol Phys       Date:  2004-01       Impact factor: 1.365

5.  The size of the EB cap determines instantaneous microtubule stability.

Authors:  Christian Duellberg; Nicholas I Cade; David Holmes; Thomas Surrey
Journal:  Elife       Date:  2016-04-06       Impact factor: 8.140

6.  An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis.

Authors:  Edward A Rietman; Douglas E Friesen; Philip Hahnfeldt; Robert Gatenby; Lynn Hlatky; Jack A Tuszynski
Journal:  Theor Biol Med Model       Date:  2013-06-10       Impact factor: 2.432

  6 in total

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