Literature DB >> 23341333

Rapid characterization of hydrogen exchange in proteins.

Anushikha Thakur1, Kousik Chandra, Abhinav Dubey, Patrick D'Silva, Hanudatta S Atreya.   

Abstract

Kinetics and thermodynamics of amide hydrogen exchange in proteins can be investigated with two-dimensional (13)CO-(15)N NMR correlation experiments. The spectra are acquired with high resolution and sensitivity. A single type of experiment on one sample serves to characterize hydrogen-deuterium fractionation factors and hydrogen-exchange rates that span three orders of magnitude.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID: 23341333     DOI: 10.1002/anie.201206828

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  4 in total

1.  High-dimensionality 13C direct-detected NMR experiments for the automatic assignment of intrinsically disordered proteins.

Authors:  Wolfgang Bermel; Isabella C Felli; Leonardo Gonnelli; Wiktor Koźmiński; Alessandro Piai; Roberta Pierattelli; Anna Zawadzka-Kazimierczuk
Journal:  J Biomol NMR       Date:  2013-11-08       Impact factor: 2.835

2.  Mechanistic Origins of Enzyme Activation in Human Glucokinase Variants Associated with Congenital Hyperinsulinism.

Authors:  Shawn M Sternisha; Peilu Liu; Alan G Marshall; Brian G Miller
Journal:  Biochemistry       Date:  2018-02-20       Impact factor: 3.162

3.  IGF-dependent dynamic modulation of a protease cleavage site in the intrinsically disordered linker domain of human IGFBP2.

Authors:  Garima Jaipuria; Divya Shet; Shahid Malik; Monalisa Swain; Hanudatta S Atreya; Charles A Galea; Mark G Slomiany; Steven A Rosenzweig; Briony E Forbes; Raymond S Norton; Somnath Mondal
Journal:  Proteins       Date:  2022-04-30

Review 4.  13C Direct Detected NMR for Challenging Systems.

Authors:  Isabella C Felli; Roberta Pierattelli
Journal:  Chem Rev       Date:  2022-01-13       Impact factor: 72.087

  4 in total

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