Literature DB >> 23337584

Unspliced XBP1 controls autophagy through FoxO1.

Rene L Vidal1, Claudio Hetz.   

Abstract

Protein homeostasis in higher eukaryotes is balanced by a dynamic network of adaptive mechanisms, including the unfolded protein response (UPR) and autophagy. In a paper recently published in Cell Research, Zhu and co-workers uncover a novel biological function of the unspliced form of the UPR transcription factor XBP1 in the modulation of autophagy through the control of FoxO1 turnover.

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Year:  2013        PMID： 23337584      PMCID： PMC3616432          DOI： 10.1038/cr.2013.9

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  15 in total

1.  Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA.

Authors:  Kota Yanagitani; Yukio Kimata; Hiroshi Kadokura; Kenji Kohno
Journal:  Science       Date:  2011-01-13       Impact factor: 47.728

2.  Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity.

Authors:  Ying Zhao; Jing Yang; Wenjuan Liao; Xiangyu Liu; Hui Zhang; Shan Wang; Donglai Wang; Jingnan Feng; Li Yu; Wei-Guo Zhu
Journal:  Nat Cell Biol       Date:  2010-06-13       Impact factor: 28.824

3.  IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA.

Authors:  Marcella Calfon; Huiqing Zeng; Fumihiko Urano; Jeffery H Till; Stevan R Hubbard; Heather P Harding; Scott G Clark; David Ron
Journal:  Nature       Date:  2002-01-03       Impact factor: 49.962

4.  Autophagy is activated for cell survival after endoplasmic reticulum stress.

Authors:  Maiko Ogata; Shin-ichiro Hino; Atsushi Saito; Keisuke Morikawa; Shinichi Kondo; Soshi Kanemoto; Tomohiko Murakami; Manabu Taniguchi; Ichiro Tanii; Kazuya Yoshinaga; Sadao Shiosaka; James A Hammarback; Fumihiko Urano; Kazunori Imaizumi
Journal:  Mol Cell Biol       Date:  2006-10-09       Impact factor: 4.272

5.  JNK regulates FoxO-dependent autophagy in neurons.

Authors:  Ping Xu; Madhumita Das; Judith Reilly; Roger J Davis
Journal:  Genes Dev       Date:  2011-02-15       Impact factor: 11.361

6.  Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer.

Authors:  Michael P A Davies; Dong Liu Barraclough; Ceri Stewart; Kathryn A Joyce; Richard M Eccles; Roger Barraclough; Philip S Rudland; David Ross Sibson
Journal:  Int J Cancer       Date:  2008-07-01       Impact factor: 7.396

7.  Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation.

Authors:  Ami Navon; Ariel Gatushkin; Lior Zelcbuch; Shimon Shteingart; Marganit Farago; Rivka Hadar; Boaz Tirosh
Journal:  FEBS Lett       Date:  2010-01-04       Impact factor: 4.124

8.  XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.

Authors:  Claudio Hetz; Peter Thielen; Soledad Matus; Melissa Nassif; Felipe Court; Roberta Kiffin; Gabriela Martinez; Ana María Cuervo; Robert H Brown; Laurie H Glimcher
Journal:  Genes Dev       Date:  2009-09-17       Impact factor: 11.361

9.  Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.

Authors:  Kota Yanagitani; Yusuke Imagawa; Takao Iwawaki; Akira Hosoda; Michiko Saito; Yukio Kimata; Kenji Kohno
Journal:  Mol Cell       Date:  2009-04-24       Impact factor: 17.970

10.  pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response.

Authors:  Hiderou Yoshida; Masaya Oku; Mie Suzuki; Kazutoshi Mori
Journal:  J Cell Biol       Date:  2006-02-06       Impact factor: 10.539
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  12 in total

Review 1.  HLA-B27 misfolding and ankylosing spondylitis.

Authors:  Robert A Colbert; Tri M Tran; Gerlinde Layh-Schmitt
Journal:  Mol Immunol       Date:  2013-08-30       Impact factor: 4.407

Review 2.  The return of the nucleus: transcriptional and epigenetic control of autophagy.

Authors:  Jens Füllgrabe; Daniel J Klionsky; Bertrand Joseph
Journal:  Nat Rev Mol Cell Biol       Date:  2013-12-11       Impact factor: 94.444

Review 3.  An evolutionary perspective on immunometabolism.

Authors:  Andrew Wang; Harding H Luan; Ruslan Medzhitov
Journal:  Science       Date:  2019-01-11       Impact factor: 47.728

Review 4.  The unfolded protein response in skeletal development and homeostasis.

Authors:  Keisuke Horiuchi; Takahide Tohmonda; Hideo Morioka
Journal:  Cell Mol Life Sci       Date:  2016-03-22       Impact factor: 9.261

Review 5.  How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy.

Authors:  Yuchen Feng; Zhiyuan Yao; Daniel J Klionsky
Journal:  Trends Cell Biol       Date:  2015-03-08       Impact factor: 20.808

6.  Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells.

Authors:  Yawei Shi; Yang Zhao; Nan Shao; Runyi Ye; Yin Lin; Ning Zhang; Wen Li; Yunjian Zhang; Shenming Wang
Journal:  Oncol Lett       Date:  2017-04-11       Impact factor: 2.967

7.  BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

Authors:  Scott J Bultman; Darcy Wood Holley; Gustaaf G de Ridder; Salvatore V Pizzo; Tatiana N Sidorova; Katherine T Murray; Brian C Jensen; Zhongjing Wang; Ariana Bevilacqua; Xin Chen; Megan T Quintana; Manasi Tannu; Gary B Rosson; Kumar Pandya; Monte S Willis
Journal:  Cardiovasc Pathol       Date:  2016-03-04       Impact factor: 2.185

8.  Deficiency of the IRE1α-Autophagy Axis Enhances the Antitumor Effects of the Oncolytic Virus M1.

Authors:  Kai Li; Cheng Hu; Fan Xing; Mingshi Gao; Jiankai Liang; Xiao Xiao; Jing Cai; Yaqian Tan; Jun Hu; Wenbo Zhu; Wei Yin; Yuan Li; Wenli Chen; Bingzheng Lu; Jialuo Mai; Pengxin Qiu; Xingwen Su; Guangmei Yan; Haipeng Zhang; Yuan Lin
Journal:  J Virol       Date:  2018-02-26       Impact factor: 5.103

9.  XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells.

Authors:  Akihiro Kishino; Ken Hayashi; Chiaki Hidai; Takeshi Masuda; Yasuyuki Nomura; Takeshi Oshima
Journal:  Sci Rep       Date:  2017-06-30       Impact factor: 4.379

10.  Annexin A2 regulates unfolded protein response via IRE1-XBP1 axis in macrophages during P. aeruginosa infection.

Authors:  Chuan-Min Zhou; Li-Mei Luo; Ping Lin; Qinqin Pu; Biao Wang; Shugang Qin; Qun Wu; Xue-Jie Yu; Min Wu
Journal:  J Leukoc Biol       Date:  2020-11-22       Impact factor: 6.011
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