Literature DB >> 23336455

Evaluation of risk assessment tools for suspected cancer in general practice: a cohort study.

William Hamilton1, Trish Green, Tanimola Martins, Kathy Elliott, Greg Rubin, Una Macleod.   

Abstract

BACKGROUND: Diagnostic delay is deemed to account for an estimated 5000 to 10 000 extra cancer deaths each year in the UK. Many cancer patients do not have symptoms meeting national referral criteria for rapid investigation. Risk assessment tools (RATs) have been developed to assist GPs in selecting patient for cancer investigation. AIM: To assess the usability and acceptability of lung and colorectal RATs, as well as subsequent resource use and cancer diagnoses. DESIGN AND
SETTING: Cohort study with nested qualitative study with 614 GPs from 165 practices in seven English cancer networks were provided with RATs applicable to patients aged ≥40 years with bowel or respiratory symptoms. In-depth interviews were conducted with 34 individuals (11 project managers and 23 GPs).
METHOD: The study measured the number of RATs used, and subsequent cancer investigations and diagnoses, over a 6-month period and compared these with the previous 6 months.
RESULTS: A total of 2593 RATs (1160 lung, 1433 colorectal) were completed. Compared with the preceding 6 months, there were 292 more chest X-rays, 104 extra 2-week chest clinic appointments, and 47 additional diagnoses of lung cancer. For suspected colorectal cancer, there were 304 more 2-week referrals, 270 more colonoscopies, and 10 more cancers identified. RATs appeared to help GPs in their selection of patients for cancer investigation. Users reported that RATs helped to confirm a need for investigation as well as allowing reassurance when investigation was not needed.
CONCLUSION: Use of RATs in primary care was accompanied by increased diagnostic activity and additional cancer diagnoses.

Entities:  

Mesh:

Year:  2013        PMID: 23336455      PMCID: PMC3529290          DOI: 10.3399/bjgp13X660751

Source DB:  PubMed          Journal:  Br J Gen Pract        ISSN: 0960-1643            Impact factor:   5.386


  10 in total

1.  Negative chest X-rays in primary care patients with lung cancer.

Authors:  Sally Stapley; Deborah Sharp; William Hamilton
Journal:  Br J Gen Pract       Date:  2006-08       Impact factor: 5.386

2.  The diagnostic performance of scoring systems to identify symptomatic colorectal cancer compared to current referral guidance.

Authors:  Tom Marshall; Robert Lancashire; Debbie Sharp; Tim J Peters; K K Cheng; William Hamilton
Journal:  Gut       Date:  2011-02-25       Impact factor: 23.059

Review 3.  Cancer diagnosis in primary care.

Authors:  William Hamilton
Journal:  Br J Gen Pract       Date:  2010-02       Impact factor: 5.386

4.  Accuracy of CT colonography for detection of large adenomas and cancers.

Authors:  C Daniel Johnson; Mei-Hsiu Chen; Alicia Y Toledano; Jay P Heiken; Abraham Dachman; Mark D Kuo; Christine O Menias; Betina Siewert; Jugesh I Cheema; Richard G Obregon; Jeff L Fidler; Peter Zimmerman; Karen M Horton; Kevin Coakley; Revathy B Iyer; Amy K Hara; Robert A Halvorsen; Giovanna Casola; Judy Yee; Benjamin A Herman; Lawrence J Burgart; Paul J Limburg
Journal:  N Engl J Med       Date:  2008-09-18       Impact factor: 91.245

5.  Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995-2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data.

Authors:  M P Coleman; D Forman; H Bryant; J Butler; B Rachet; C Maringe; U Nur; E Tracey; M Coory; J Hatcher; C E McGahan; D Turner; L Marrett; M L Gjerstorff; T B Johannesen; J Adolfsson; M Lambe; G Lawrence; D Meechan; E J Morris; R Middleton; J Steward; M A Richards
Journal:  Lancet       Date:  2010-12-21       Impact factor: 79.321

6.  The mortality of colorectal cancer in relation to the initial symptom at presentation to primary care and to the duration of symptoms: a cohort study using medical records.

Authors:  S Stapley; T J Peters; D Sharp; W Hamilton
Journal:  Br J Cancer       Date:  2006-10-24       Impact factor: 7.640

7.  What if cancer survival in Britain were the same as in Europe: how many deaths are avoidable?

Authors:  M Abdel-Rahman; D Stockton; B Rachet; T Hakulinen; M P Coleman
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

8.  The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients.

Authors:  W Hamilton
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

9.  The size of the prize for earlier diagnosis of cancer in England.

Authors:  M A Richards
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

10.  Clinical features of colorectal cancer before diagnosis: a population-based case-control study.

Authors:  W Hamilton; A Round; D Sharp; T J Peters
Journal:  Br J Cancer       Date:  2005-08-22       Impact factor: 7.640

  10 in total
  55 in total

Review 1.  RATs: Quality not Quantity.

Authors:  Joseph Anthony
Journal:  Br J Gen Pract       Date:  2015-07       Impact factor: 5.386

Review 2.  Lung cancer in symptomatic patients presenting in primary care: a systematic review of risk prediction tools.

Authors:  Mia Schmidt-Hansen; Sabine Berendse; Willie Hamilton; David R Baldwin
Journal:  Br J Gen Pract       Date:  2017-05-08       Impact factor: 5.386

3.  Improving early diagnosis of cancer in UK general practice.

Authors:  Ian Morgan; Scott Wilkes
Journal:  Br J Gen Pract       Date:  2017-06       Impact factor: 5.386

Review 4.  Improving early diagnosis of symptomatic cancer.

Authors:  Willie Hamilton; Fiona M Walter; Greg Rubin; Richard D Neal
Journal:  Nat Rev Clin Oncol       Date:  2016-07-26       Impact factor: 66.675

5.  Cancer diagnostic tools to aid decision-making in primary care: mixed-methods systematic reviews and cost-effectiveness analysis.

Authors:  Antonieta Medina-Lara; Bogdan Grigore; Ruth Lewis; Jaime Peters; Sarah Price; Paolo Landa; Sophie Robinson; Richard Neal; William Hamilton; Anne E Spencer
Journal:  Health Technol Assess       Date:  2020-11       Impact factor: 4.014

6.  Identification of patients with non-metastatic colorectal cancer in primary care: a case-control study.

Authors:  Marcela Ewing; Peter Naredi; Chenyang Zhang; Jörgen Månsson
Journal:  Br J Gen Pract       Date:  2016-11-07       Impact factor: 5.386

7.  Strategies to accelerate diagnosis of primary brain tumors at the primary-secondary care interface in children and adults.

Authors:  David Walker; Willie Hamilton; Fiona M Walter; Colin Watts
Journal:  CNS Oncol       Date:  2013-09

8.  A symptom-based model to predict colorectal cancer in low-resource countries: Results from a prospective study of patients at high risk for colorectal cancer.

Authors:  Olusegun Isaac Alatise; Omobolaji O Ayandipo; Ademola Adeyeye; Ken Seier; Akinwunmi O Komolafe; Matthew O Bojuwoye; Oludapo O Afuwape; Ann Zauber; Adeleye Omisore; Samuel Olatoke; Adegboyega Akere; Olusola Famurewa; Mithat Gonen; David O Irabor; T Peter Kingham
Journal:  Cancer       Date:  2018-04-12       Impact factor: 6.860

9.  Risk of uterine cancer in symptomatic women in primary care: case-control study using electronic records.

Authors:  Sarah Walker; Chris Hyde; William Hamilton
Journal:  Br J Gen Pract       Date:  2013-09       Impact factor: 5.386

10.  Anaemia as a risk stratification tool for symptomatic patients referred via the two-week wait pathway for colorectal cancer.

Authors:  S Mashlab; P Large; W Laing; O Ng; M D'Auria; D Thurston; S Thomson; A G Acheson; D J Humes; A Banerjea
Journal:  Ann R Coll Surg Engl       Date:  2018-03-15       Impact factor: 1.891

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.