Literature DB >> 23332584

Glucagon-like peptide 1 and appetite.

Megan J Dailey1, Timothy H Moran.   

Abstract

Glucagon-like peptide 1 (GLP-1) and GLP-1 analogs have received much recent attention due to the success of GLP-1 mimetics in treating type II diabetes mellitus (T2DM), but these compounds may also have the potential to treat obesity. The satiety effect of GLP-1 may involve both within-meal enteroenteric reflexes, and across-meal central signaling mechanisms, that mediate changes in appetite and promote satiety. Here, we review data supporting the role of both peripheral and central GLP-1 signaling in the control of gastrointestinal motility and food intake. Understanding the mechanisms underlying the appetite-suppressive effects of GLP-1 may help in developing targeted treatments for obesity.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID： 23332584      PMCID： PMC3594872          DOI： 10.1016/j.tem.2012.11.008

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  77 in total

1.  Circulating GLP-1 and CCK-8 reduce food intake by capsaicin-insensitive, nonvagal mechanisms.

Authors:  Jingchuan Zhang; Robert C Ritter
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-10-26       Impact factor: 3.619

2.  Cholinergic stimulation enhances colonic motor activity, transit, and sensation in humans.

Authors:  N M Law; A E Bharucha; A S Undale; A R Zinsmeister
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2001-11       Impact factor: 4.052

3.  Enhanced GLP-1- and sulfonylurea-induced insulin secretion in islets lacking leptin signaling.

Authors:  Tomoaki Morioka; John F Dishinger; Kendra R Reid; Chong Wee Liew; Ting Zhang; Masaaki Inaba; Robert T Kennedy; Rohit N Kulkarni
Journal:  Mol Endocrinol       Date:  2012-04-03

4.  Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.

Authors:  L Hansen; C F Deacon; C Orskov; J J Holst
Journal:  Endocrinology       Date:  1999-11       Impact factor: 4.736

5.  Disassociation between preprandial gut peptide release and food-anticipatory activity.

Authors:  Megan J Dailey; Katherine C Stingl; Timothy H Moran
Journal:  Endocrinology       Date:  2011-11-29       Impact factor: 4.736

6.  Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.

Authors:  E Rask; T Olsson; S Söderberg; O Johnson; J Seckl; J J Holst; B Ahrén
Journal:  Diabetes Care       Date:  2001-09       Impact factor: 19.112

7.  A human cellular model for studying the regulation of glucagon-like peptide-1 secretion.

Authors:  R A Reimer; C Darimont; S Gremlich; V Nicolas-Métral; U T Rüegg; K Macé
Journal:  Endocrinology       Date:  2001-10       Impact factor: 4.736

8.  A functional role for central glucagon-like peptide-1 receptors in lithium chloride-induced anorexia.

Authors:  L Rinaman
Journal:  Am J Physiol       Date:  1999-11

9.  Glucagon-like peptide (GLP-1) is involved in the central modulation of fecal output in rats.

Authors:  M A Gülpinar; A Bozkurt; T Coşkun; N B Ulusoy; B C Yegen
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2000-06       Impact factor: 4.052

10.  Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism.

Authors:  Masayuki Miyazaki; Masaki Kato; Kosuke Tanaka; Masatake Tanaka; Motoyuki Kohjima; Kazuhiko Nakamura; Munechika Enjoji; Makoto Nakamuta; Kazuhiro Kotoh; Ryoichi Takayanagi
Journal:  Mol Med Rep       Date:  2011-12-13       Impact factor: 2.952
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  55 in total

1.  Nutrient-specific feeding and endocrine effects of jejunal infusions in obese animals.

Authors:  Megan J Dailey; Alexander A Moghadam; Timothy H Moran
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2014-01-22       Impact factor: 3.619

2.  Incretin-based therapies and pancreatitis risk: myth or reality.

Authors:  Joseph M Pappachan
Journal:  Endocrine       Date:  2014-11-30       Impact factor: 3.633

3.  Genetic variability in GLP-1 receptor is associated with inter-individual differences in weight lowering potential of liraglutide in obese women with PCOS: a pilot study.

Authors:  Mojca Jensterle; Boštjan Pirš; Katja Goričar; Vita Dolžan; Andrej Janež
Journal:  Eur J Clin Pharmacol       Date:  2015-05-21       Impact factor: 2.953

4.  Increased nutrient sensitivity and plasma concentrations of enteral hormones during duodenal nutrient infusion in functional dyspepsia.

Authors:  Adil E Bharucha; Michael Camilleri; Duane D Burton; Shannon L Thieke; Kelly J Feuerhak; Ananda Basu; Alan R Zinsmeister
Journal:  Am J Gastroenterol       Date:  2014-11-18       Impact factor: 10.864

Review 5.  A view of obesity as a learning and memory disorder.

Authors:  Terry L Davidson; Andrea L Tracy; Lindsey A Schier; Susan E Swithers
Journal:  J Exp Psychol Anim Learn Cogn       Date:  2014-07       Impact factor: 2.478

6.  Preclinical relevance of probiotics in type 2 diabetes: A systematic review.

Authors:  Anaísa Martins Marques; Mariáurea Matias Sarandy; Rômulo Dias Novaes; Reggiani Vilela Gonçalves; Mariella Bontempo Freitas
Journal:  Int J Exp Pathol       Date:  2020-07-01       Impact factor: 1.925

7.  Binge-like palatable food intake in rats reduces preproglucagon in the nucleus tractus solitarius.

Authors:  Ashmita Mukherjee; Avery Hum; Tyler J Gustafson; Elizabeth G Mietlicki-Baase
Journal:  Physiol Behav       Date:  2020-02-13

8.  Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury.

Authors:  Nigel H Greig; David Tweedie; Lital Rachmany; Yazhou Li; Vardit Rubovitch; Shaul Schreiber; Yung-Hsiao Chiang; Barry J Hoffer; Jonathan Miller; Debomoy K Lahiri; Kumar Sambamurti; Robert E Becker; Chaim G Pick
Journal:  Alzheimers Dement       Date:  2014-02       Impact factor: 21.566

Review 9.  Effects of GLP-1 on appetite and weight.

Authors:  Meera Shah; Adrian Vella
Journal:  Rev Endocr Metab Disord       Date:  2014-09       Impact factor: 6.514

10.  Effect of diet type and added copper on growth performance, carcass characteristics, energy digestibility, gut morphology, and mucosal mRNA expression of finishing pigs.

Authors:  Kyle F Coble; Derris D Burnett; Joel M DeRouchey; Mike D Tokach; John M Gonzalez; Fangzhou Wu; Steve S Dritz; Robert D Goodband; Jason C Woodworth; John R Pluske
Journal:  J Anim Sci       Date:  2018-07-28       Impact factor: 3.159
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