Literature DB >> 23332453

Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy.

Rocky Pramanik1, Xia Sheng, Brian Ichihara, Nora Heisterkamp, Steven D Mittelman.   

Abstract

Obesity is associated with an increased risk of acute lymphoblastic leukemia (ALL) relapse. Using mouse and cell co-culture models, we investigated whether adipose tissue attracts ALL to a protective microenvironment. Syngeneically implanted ALL cells migrated into adipose tissue within ten days. In vitro, murine ALL cells migrated towards adipose tissue explants and 3T3-L1 adipocytes. Human and mouse ALL cells migrated toward adipocyte conditioned media, which was mediated by SDF-1α. In addition, adipose tissue explants protected ALL cells against daunorubicin and vincristine. Our findings suggest that ALL migration into adipose tissue could contribute to drug resistance and potentially relapse.
Copyright © 2012 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23332453      PMCID： PMC3622767          DOI： 10.1016/j.leukres.2012.12.013

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  49 in total

1.  B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.

Authors:  Daniel A Winer; Shawn Winer; Lei Shen; Persis P Wadia; Jason Yantha; Geoffrey Paltser; Hubert Tsui; Ping Wu; Matthew G Davidson; Michael N Alonso; Hwei X Leong; Alec Glassford; Maria Caimol; Justin A Kenkel; Thomas F Tedder; Tracey McLaughlin; David B Miklos; H-Michael Dosch; Edgar G Engleman
Journal:  Nat Med       Date:  2011-04-17       Impact factor: 53.440

Review 2.  Biology, risk stratification, and therapy of pediatric acute leukemias: an update.

Authors:  Ching-Hon Pui; William L Carroll; Soheil Meshinchi; Robert J Arceci
Journal:  J Clin Oncol       Date:  2011-01-10       Impact factor: 44.544

3.  Targeted label-free quantitative analysis of secretory proteins from adipocytes in response to oxidative stress.

Authors:  Sunkyu Choi; Jaeyoon Kim; Kyungmoo Yea; Pann-Ghill Suh; Jeongkwon Kim; Sung Ho Ryu
Journal:  Anal Biochem       Date:  2010-03-10       Impact factor: 3.365

4.  A functional receptor for B-cell-activating factor is expressed on human acute lymphoblastic leukemias.

Authors:  Reshmi Parameswaran; Markus Müschen; Yong-Mi Kim; John Groffen; Nora Heisterkamp
Journal:  Cancer Res       Date:  2010-05-11       Impact factor: 12.701

Review 5.  Can inhibition of the SDF-1/CXCR4 axis eradicate acute leukemia?

Authors:  Sigal Tavor; Isabelle Petit
Journal:  Semin Cancer Biol       Date:  2010-07-15       Impact factor: 15.707

6.  Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance.

Authors:  Antonina V Kurtova; Kumudha Balakrishnan; Rong Chen; Wei Ding; Susanne Schnabl; Maite P Quiroga; Mariela Sivina; William G Wierda; Zeev Estrov; Michael J Keating; Medhat Shehata; Ulrich Jäger; Varsha Gandhi; Neil E Kay; William Plunkett; Jan A Burger
Journal:  Blood       Date:  2009-09-17       Impact factor: 22.113

Review 7.  Biological mechanisms linking obesity and cancer risk: new perspectives.

Authors:  Darren L Roberts; Caroline Dive; Andrew G Renehan
Journal:  Annu Rev Med       Date:  2010       Impact factor: 13.739

8.  Development of resistance to dasatinib in Bcr/Abl-positive acute lymphoblastic leukemia.

Authors:  F Fei; S Stoddart; M Müschen; Y-m Kim; J Groffen; N Heisterkamp
Journal:  Leukemia       Date:  2010-01-28       Impact factor: 11.528

Review 9.  Obesity and cancer.

Authors:  Kathleen Y Wolin; Kenneth Carson; Graham A Colditz
Journal:  Oncologist       Date:  2010-05-27

10.  Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells.

Authors:  Monica Bartucci; Susanne Svensson; Lucia Ricci-Vitiani; Rosanna Dattilo; Mauro Biffoni; Michele Signore; Rita Ferla; Ruggero De Maria; Eva Surmacz
Journal:  Endocr Relat Cancer       Date:  2010-08-16       Impact factor: 5.678
View more
  34 in total

1.  Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group.

Authors:  Etan Orgel; Richard Sposto; Jemily Malvar; Nita L Seibel; Elena Ladas; Paul S Gaynon; David R Freyer
Journal:  J Clin Oncol       Date:  2014-03-31       Impact factor: 44.544

Review 2.  Adipocyte and lipid metabolism in cancer drug resistance.

Authors:  Yihai Cao
Journal:  J Clin Invest       Date:  2019-07-02       Impact factor: 14.808

3.  Adipocytes enhance expression of osteoclast adhesion-related molecules through the CXCL12/CXCR4 signalling pathway.

Authors:  Tingting Luo; Hongrui Liu; Wei Feng; Di Liu; Juan Du; Jing Sun; Wei Wang; Xiuchun Han; Jie Guo; Norio Amizuka; Xianqi Li; Minqi Li
Journal:  Cell Prolif       Date:  2016-11-21       Impact factor: 6.831

Review 4.  Role of bone marrow adipocytes in leukemia and chemotherapy challenges.

Authors:  Azin Samimi; Majid Ghanavat; Saeid Shahrabi; Shirin Azizidoost; Najmaldin Saki
Journal:  Cell Mol Life Sci       Date:  2019-02-04       Impact factor: 9.261

5.  Mechanisms by Which Obesity Impacts Survival from Acute Lymphoblastic Leukemia.

Authors:  Etan Orgel; Jessica L Sea; Steven D Mittelman
Journal:  J Natl Cancer Inst Monogr       Date:  2019-09-01

6.  Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia.

Authors:  Xavier Cahu; Julien Calvo; Sandrine Poglio; Nais Prade; Benoit Colsch; Marie-Laure Arcangeli; Thierry Leblanc; Arnaud Petit; Frederic Baleydier; Andre Baruchel; Judith Landman-Parker; Christophe Junot; Jerome Larghero; Paola Ballerini; Eric Delabesse; Benjamin Uzan; Francoise Pflumio
Journal:  Blood Adv       Date:  2017-09-08

7.  Human Adipose Tissue Stem Cells Promote the Growth of Acute Lymphoblastic Leukemia Cells in NOD/SCID Mice.

Authors:  Myoung Woo Lee; Yoo Jin Park; Dae Seong Kim; Hyun Jin Park; Hye Lim Jung; Ji Won Lee; Ki Woong Sung; Hong Hoe Koo; Keon Hee Yoo
Journal:  Stem Cell Rev Rep       Date:  2018-06       Impact factor: 5.739

8.  Adipocytes as a critical component of the tumor microenvironment.

Authors:  Linda Vona-Davis; Laura F Gibson
Journal:  Leuk Res       Date:  2013-02-04       Impact factor: 3.156

9.  Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin.

Authors:  Xia Sheng; Jean-Hugues Parmentier; Jonathan Tucci; Hua Pei; Omar Cortez-Toledo; Christina M Dieli-Conwright; Matthew J Oberley; Michael Neely; Etan Orgel; Stan G Louie; Steven D Mittelman
Journal:  Mol Cancer Res       Date:  2017-11-08       Impact factor: 5.852

Review 10.  Immunotoxins for leukemia.

Authors:  Alan S Wayne; David J Fitzgerald; Robert J Kreitman; Ira Pastan
Journal:  Blood       Date:  2014-02-27       Impact factor: 22.113
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.