Literature DB >> 23328892

Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project.

Lisa A Cannon-Albright1, Sue Dintelman, Tim Maness, Steve Backus, Alun Thomas, Laurence J Meyer.   

Abstract

PURPOSE: Creation of a genealogy of the United States and its ancestral populations is under way. When complete, this US genealogy will be record linked to the National Veteran's Health Administration medical data representing more than 8 million US veterans.
METHODS: Genealogical data are gathered from public sources, primarily the Internet. Record linking using data from relatives is accomplished to integrate multiple data sources and then to link genealogical data to the veteran's demographic data.
RESULTS: This resource currently includes genealogy for more than 22 million individuals representing the Intermountain West and the East Coast. The demographic data for more than 40,000 veteran patients using Veterans Hospital Administration services in Utah and Massachusetts have already been record linked.
CONCLUSION: The resource is only in its second year of creation and already represents the largest such combination of genealogy and medical data in the world. The data sources, the creation of the genealogy, record-linking methods and results, proposed genetic analyses, and future directions are discussed.

Entities:  

Mesh:

Year:  2013        PMID: 23328892     DOI: 10.1038/gim.2012.171

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  5 in total

Review 1.  Ancestry Testing and the Practice of Genetic Counseling.

Authors:  Brianne E Kirkpatrick; Misha D Rashkin
Journal:  J Genet Couns       Date:  2016-10-04       Impact factor: 2.537

2.  Electronically ascertained extended pedigrees in breast cancer genetic counseling.

Authors:  V Stefansdottir; H Skirton; O Th Johannsson; H Olafsdottir; G H Olafsdottir; L Tryggvadottir; J J Jonsson
Journal:  Fam Cancer       Date:  2019-04       Impact factor: 2.375

Review 3.  Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.

Authors:  Michele Carbone; Ivano Amelio; El Bachir Affar; James Brugarolas; Lisa A Cannon-Albright; Lewis C Cantley; Webster K Cavenee; Zhijian Chen; Carlo M Croce; Alan D' Andrea; David Gandara; Carlotta Giorgi; Wei Jia; Qing Lan; Tak Wah Mak; James L Manley; Katsuhiko Mikoshiba; Jose N Onuchic; Harvey I Pass; Paolo Pinton; Carol Prives; Nathaniel Rothman; Said M Sebti; James Turkson; Xifeng Wu; Haining Yang; Herbert Yu; Gerry Melino
Journal:  Cell Death Differ       Date:  2018-10-15       Impact factor: 15.828

4.  Evidence for an Inherited Contribution to Sepsis Susceptibility Among a Cohort of U.S. Veterans.

Authors:  Jordan A Kempker; Greg S Martin; Matthew T Rondina; Lisa A Cannon-Albright
Journal:  Crit Care Explor       Date:  2022-01-11

5.  Population genealogy resource shows evidence of familial clustering for Alzheimer disease.

Authors:  Lisa Anne Cannon-Albright; Sue Dintelman; Tim Maness; Johni Cerny; Alun Thomas; Steven Backus; James Michael Farnham; Craig Carl Teerlink; Jorge Contreras; John S K Kauwe; Laurence J Meyer
Journal:  Neurol Genet       Date:  2018-08-01
  5 in total

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