Literature DB >> 23322390

The neonatal autopsy: can it be revived?

Cameron H Swinton1, Julie Weiner, Felix A Okah.   

Abstract

OBJECTIVES: To describe the trend and factors associated with the autopsy over the past decade at a level III neonatal intensive care unit (NICU) where all patients are presented with an option. STUDY
DESIGN: Retrospective study of the autopsy in a cohort of infants who died in the NICU from January 1, 2001, to December 31, 2010.
RESULTS: Of 446 deaths, 33.9% received the autopsy and rates decreased from the 2 years prior to the study. The autopsy was associated with gestational age at birth and chronologic age at death. On multivariable logistic regression analyses, the odds of an autopsy increased with gestational age (p = 0.001), death in the postneonatal period (odds ratio [OR] = 2.01, 95% confidence interval [CI] = 1.28, 3.16), and absence of a major congenital anomaly (OR = 1.96, 95% CI = 1.22, 3.23).
CONCLUSION: Autopsy rates continue to decline despite ensuring that all parents are presented with the option. Infants born at term and those who die after 1 month without known congenital anomalies are most likely to receive the autopsy. The persistently low rates may highlight the importance of helping families understand that the autopsy has utility even when the cause of death may appear to be obvious. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Entities:  

Mesh:

Year:  2013        PMID: 23322390     DOI: 10.1055/s-0032-1332798

Source DB:  PubMed          Journal:  Am J Perinatol        ISSN: 0735-1631            Impact factor:   1.862


  8 in total

1.  Running a postmortem service--a business case and clinical experience.

Authors:  Marta C Cohen; Elspeth Whitby; Michelle A Fink; Jacquelene M Collett; Amaka C Offiah
Journal:  Pediatr Radiol       Date:  2015-04-01

2.  Value of postmortem studies in deceased neonatal and pediatric intensive care unit patients.

Authors:  Raphael Widmann; Rosmarie Caduff; Luca Giudici; Qing Zhong; Alexander Vogetseder; Romaine Arlettaz; Bernhard Frey; Holger Moch; Peter K Bode
Journal:  Virchows Arch       Date:  2016-12-14       Impact factor: 4.064

3.  The Value of Autopsy in Neonates in the 21st Century.

Authors:  Joline L H de Sévaux; Peter G J Nikkels; Maarten H Lequin; Floris Groenendaal
Journal:  Neonatology       Date:  2018-10-23       Impact factor: 4.035

4.  Factors affecting uptake of postmortem examination in the prenatal, perinatal and paediatric setting.

Authors:  C Lewis; M Hill; O J Arthurs; C Hutchinson; L S Chitty; N J Sebire
Journal:  BJOG       Date:  2017-03-21       Impact factor: 6.531

Review 5.  The Practicality of Post-mortem Imaging in Prenatal, Perinatal, and Pediatric Cases.

Authors:  Christina Ashby; Abrahim N Razzak; Ann Kogler; Ahmad Amireh; John Dempsey; Keldon K Lin; Joseph Waller; Pinky Jha
Journal:  Cureus       Date:  2022-09-06

6.  Minimally invasive, imaging guided virtual autopsy compared to conventional autopsy in foetal, newborn and infant cases: study protocol for the paediatric virtual autopsy trial.

Authors:  Christoph M Rüegger; Christine Bartsch; Rosa Maria Martinez; Steffen Ross; Stephan A Bolliger; Brigitte Koller; Leonhard Held; Elisabeth Bruder; Peter Karl Bode; Rosmarie Caduff; Bernhard Frey; Leonhard Schäffer; Hans Ulrich Bucher
Journal:  BMC Pediatr       Date:  2014-01-20       Impact factor: 2.125

Review 7.  Paediatric and perinatal postmortem imaging: the need for a subspecialty approach.

Authors:  Owen J Arthurs; Rick R van Rijn; Andrew M Taylor; Neil J Sebire
Journal:  Pediatr Radiol       Date:  2014-08-30

8.  Postmortem magnetic resonance appearances of congenital high airway obstruction syndrome.

Authors:  Owen J Arthurs; Lyn S Chitty; Lydia Judge-Kronis; Neil J Sebire
Journal:  Pediatr Radiol       Date:  2014-09-05
  8 in total

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