STUDY OBJECTIVES: To evaluate for the first night effect (FNE) in a group of young children with autism. DESIGN: Analysis of polysomnographic data from a 2-night sleep laboratory study. SETTING: Clinical Center of the National Institutes of Health. PATIENTS OR PARTICIPANTS: 15 children (aged 2-10 years) with a diagnosis of an ASD. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Polysomnographic analysis showed the presence of a FNE for wake after sleep onset minutes, stage 2, and sleep efficiency, but not for REM sleep parameters or TST. CONCLUSIONS: In this 2-night polysomnographic analysis of sleep stages in young children with autism, we did not find the expected second night increase in total sleep time or REM sleep percentage or a decrease in REM sleep latency. This lack of an FNE for TST and REM parameters suggests that a single-night polysomnogram may be sufficient to evaluate children with an ASD for TST or REM parameters.
STUDY OBJECTIVES: To evaluate for the first night effect (FNE) in a group of young children with autism. DESIGN: Analysis of polysomnographic data from a 2-night sleep laboratory study. SETTING: Clinical Center of the National Institutes of Health. PATIENTS OR PARTICIPANTS: 15 children (aged 2-10 years) with a diagnosis of an ASD. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Polysomnographic analysis showed the presence of a FNE for wake after sleep onset minutes, stage 2, and sleep efficiency, but not for REM sleep parameters or TST. CONCLUSIONS: In this 2-night polysomnographic analysis of sleep stages in young children with autism, we did not find the expected second night increase in total sleep time or REM sleep percentage or a decrease in REM sleep latency. This lack of an FNE for TST and REM parameters suggests that a single-night polysomnogram may be sufficient to evaluate children with an ASD for TST or REM parameters.
Authors: R E Dahl; N D Ryan; B Birmaher; M al-Shabbout; D E Williamson; M Neidig; B Nelson; J Puig-Antich Journal: Psychiatry Res Date: 1991-08 Impact factor: 3.222
Authors: Michelle Primeau; Anda Gershon; Lisa Talbot; Isabelle Cotto; Linda Lotspeich; Antonio Hardan; Joachim Hallmayer; Ruth O'Hara Journal: J Clin Sleep Med Date: 2016-03 Impact factor: 4.062
Authors: Cristan A Farmer; Priyanka Chilakamarri; Audrey E Thurm; Susan E Swedo; Gregory L Holmes; Ashura W Buckley Journal: Neurology Date: 2018-06-06 Impact factor: 9.910