| Literature DB >> 2331751 |
K E Joho1, M K Darby, E T Crawford, D D Brown.
Abstract
A 5S RNA binding protein (p43) in Xenopus is a major constituent of oocytes and comprises part of a 42S ribonucleoprotein storage particle. We have cloned and sequenced p43 cDNA from X. laevis and X. borealis as well as the cDNA for X. borealis TFIIIA. Like TFIIIA, p43 has nine zinc fingers, seven of which are exactly the same size as their counterparts in TFIIIA. Amino acid homology between the two proteins is restricted mainly to conserved residues characteristic of zinc fingers. In contrast to TFIIIA, which binds specifically to both 5S RNA and 5S RNA genes, p43 binds exclusively to 5S RNA.Entities:
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Year: 1990 PMID： 2331751 DOI： 10.1016/0092-8674(90)90809-s
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582