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Literature DB >> 2331435

Fatty acid control of growth of human cervical and endometrial cancer cells.

R P Gleeson¹, M Ayub, J T Wright, C B Wood, N A Habib, W P Soutter, M H Sullivan, J O White.

Abstract

Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor number or affinity.

Entities: CellLine Chemical Disease Species

Mesh：

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Year: 1990 PMID： 2331435 PMCID： PMC1971358 DOI： 10.1038/bjc.1990.113

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

26 in total

1. Protein kinase C inhibition of the epidermal growth factor receptor tyrosine protein kinase activity is independent of the oligomeric state of the receptor.

Authors: I C Northwood; R J Davis
Journal: J Biol Chem Date: 1989-04-05 Impact factor: 5.157

2. The effect of cell damage on the density and steroidogenic capacity of rat testis Leydig cells, using an NADH exclusion test for determination of viability.

Authors: L F Aldred; B A Cooke
Journal: J Steroid Biochem Date: 1983-04 Impact factor: 4.292

3. Epidermal growth factor binding and protein kinase C activities in human breast cancer cell lines: possible quantitative relationship.

Authors: D Fabbro; W Küng; W Roos; R Regazzi; U Eppenberger
Journal: Cancer Res Date: 1986-06 Impact factor: 12.701

4. Epidermal growth factor stimulates the synthesis of its own receptor in a human breast cancer cell line.

Authors: J E Kudlow; C Y Cheung; J D Bjorge
Journal: J Biol Chem Date: 1986-03-25 Impact factor: 5.157

5. Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes.

Authors: I P Gladhaug; M Refsnes; T E Sand; T Christoffersen
Journal: Cancer Res Date: 1988-11-15 Impact factor: 12.701

Fatty acid control of growth of human cervical and endometrial cancer cells.

1. Protein kinase C inhibition of the epidermal growth factor receptor tyrosine protein kinase activity is independent of the oligomeric state of the receptor.

2. The effect of cell damage on the density and steroidogenic capacity of rat testis Leydig cells, using an NADH exclusion test for determination of viability.

3. Epidermal growth factor binding and protein kinase C activities in human breast cancer cell lines: possible quantitative relationship.

4. Epidermal growth factor stimulates the synthesis of its own receptor in a human breast cancer cell line.

5. Effects of butyrate on epidermal growth factor receptor binding, morphology, and DNA synthesis in cultured rat hepatocytes.

Review 6. Biological and therapeutic potential of membrane lipid modification in tumors.

7. Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer.

8. Cytotoxic effects of free fatty acids on ascites tumor cells.

9. Biological effect of epidermal growth factor on the in vitro growth of human tumors.

10. Loss of EGF binding and cation transport response during differentiation of mouse neuroblastoma cells.

1. The effect of sodium butyrate on the growth characteristics of human cervix tumour cells.

2. Antiproliferative activity of Vallaris glabra Kuntze (Apocynaceae).