Literature DB >> 23312278

Tipping the energy balance toward longevity.

William Mair1.   

Abstract

AMPK is a cellular energy sensor conserved across eukaryotes that in C. elegans prolongs life span and mimics dietary restriction. Stenesen and colleagues (2012) activate AMPK both directly and indirectly by altering AMP biosynthesis to slow aging in Drosophila, highlighting AMPK as a conserved life span modulator that links energy sensing to longevity.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Year:  2013        PMID： 23312278     DOI： 10.1016/j.cmet.2012.11.011

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  6 in total

1.  Genetic perturbation of key central metabolic genes extends lifespan in Drosophila and affects response to dietary restriction.

Authors:  Matthew E Talbert; Brittany Barnett; Robert Hoff; Maria Amella; Kate Kuczynski; Erik Lavington; Spencer Koury; Evgeny Brud; Walter F Eanes
Journal:  Proc Biol Sci       Date:  2015-09-22       Impact factor: 5.349

2.  Physiological roles for mafr-1 in reproduction and lipid homeostasis.

Authors:  Akshat Khanna; Deborah L Johnson; Sean P Curran
Journal:  Cell Rep       Date:  2014-12-11       Impact factor: 9.423

3.  ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity.

Authors:  Fu-Hui Xiao; Qin Yu; Zhi-Li Deng; Ke Yang; Yunshuang Ye; Ming-Xia Ge; Dongjing Yan; Hao-Tian Wang; Xiao-Qiong Chen; Li-Qin Yang; Bin-Yu Yang; Rong Lin; Wen Zhang; Xing-Li Yang; Lei Dong; Yonghan He; Jumin Zhou; Wang-Wei Cai; Ji Li; Qing-Peng Kong
Journal:  Sci Adv       Date:  2022-04-27       Impact factor: 14.957

4.  One-carbon metabolism: an aging-cancer crossroad for the gerosuppressant metformin.

Authors:  Javier A Menendez; Jorge Joven
Journal:  Aging (Albany NY)       Date:  2012-12       Impact factor: 5.682

5.  The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals.

Authors:  David W Johnson; Jesse R Llop; Sara F Farrell; Jie Yuan; Lindsay R Stolzenburg; Andrew V Samuelson
Journal:  PLoS Genet       Date:  2014-04-03       Impact factor: 5.917

6.  Hypodermal responses to protein synthesis inhibition induce systemic developmental arrest and AMPK-dependent survival in Caenorhabditis elegans.

Authors:  Hans M Dalton; Sean P Curran
Journal:  PLoS Genet       Date:  2018-07-18       Impact factor: 5.917
  6 in total

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