Literature DB >> 23307751

Structures of fluoro, amino, and thiol inhibitors bound to the [Fe4S4] protein IspH.

Ingrid Span1, Ke Wang, Weixue Wang, Johann Jauch, Wolfgang Eisenreich, Adelbert Bacher, Eric Oldfield, Michael Groll.   

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Year:  2013        PMID： 23307751      PMCID： PMC3734547          DOI： 10.1002/anie.201208469

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  21 in total

1.  The isoprene rule and the biogenesis of terpenic compounds.

Authors:  L RUZICKA
Journal:  Experientia       Date:  1953-10-15

2.  Bioorganometallic mechanism of action, and inhibition, of IspH.

Authors:  Weixue Wang; Ke Wang; Yi-Liang Liu; Joo-Hwan No; Jikun Li; Mark J Nilges; Eric Oldfield
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-19       Impact factor: 11.205

Review 3.  Structure, function, and formation of biological iron-sulfur clusters.

Authors:  Deborah C Johnson; Dennis R Dean; Archer D Smith; Michael K Johnson
Journal:  Annu Rev Biochem       Date:  2005       Impact factor: 23.643

4.  Mechanistic studies of IspH in the deoxyxylulose phosphate pathway: heterolytic C-O bond cleavage at C4 position.

Authors:  Youli Xiao; Zongbao K Zhao; Pinghua Liu
Journal:  J Am Chem Soc       Date:  2008-01-25       Impact factor: 15.419

5.  Biosynthesis of isoprene units: Mössbauer spectroscopy of substrate and inhibitor binding to the [4Fe-4S] cluster of the LytB/IspH enzyme.

Authors:  Annegret Ahrens-Botzong; Karnjapan Janthawornpong; Juliusz A Wolny; Erasmienne Ngouamegne Tambou; Michel Rohmer; Sergiy Krasutsky; C Dale Poulter; Volker Schünemann; Myriam Seemann
Journal:  Angew Chem Int Ed Engl       Date:  2011-10-19       Impact factor: 15.336

Review 6.  Iron-sulfur clusters: nature's modular, multipurpose structures.

Authors:  H Beinert; R H Holm; E Münck
Journal:  Science       Date:  1997-08-01       Impact factor: 47.728

7.  Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation.

Authors:  Weixue Wang; Ke Wang; Ingrid Span; Johann Jauch; Adelbert Bacher; Michael Groll; Eric Oldfield
Journal:  J Am Chem Soc       Date:  2012-06-28       Impact factor: 15.419

8.  Probing the reaction mechanism of IspH protein by x-ray structure analysis.

Authors:  Tobias Gräwert; Ingrid Span; Wolfgang Eisenreich; Felix Rohdich; Jörg Eppinger; Adelbert Bacher; Michael Groll
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-28       Impact factor: 11.205

9.  Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway.

Authors:  Ingo Rekittke; Jochen Wiesner; Rene Röhrich; Ulrike Demmer; Eberhard Warkentin; Weiya Xu; Kathrin Troschke; Martin Hintz; Joo Hwan No; Evert C Duin; Eric Oldfield; Hassan Jomaa; Ulrich Ermler
Journal:  J Am Chem Soc       Date:  2008-12-24       Impact factor: 15.419

10.  Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.

Authors:  Ingrid Span; Ke Wang; Weixue Wang; Yonghui Zhang; Adelbert Bacher; Wolfgang Eisenreich; Kai Li; Charles Schulz; Eric Oldfield; Michael Groll
Journal:  Nat Commun       Date:  2012       Impact factor: 14.919
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  9 in total

Review 1.  Bioorganometallic chemistry with IspG and IspH: structure, function, and inhibition of the [Fe(4)S(4)] proteins involved in isoprenoid biosynthesis.

Authors:  Weixue Wang; Eric Oldfield
Journal:  Angew Chem Int Ed Engl       Date:  2014-01-31       Impact factor: 15.336

2.  Isoprenoid Biosynthesis in Pathogenic Bacteria: Nuclear Resonance Vibrational Spectroscopy Provides Insight into the Unusual [4Fe-4S] Cluster of the E. coli LytB/IspH Protein.

Authors:  Isabelle Faus; Annegret Reinhard; Sergej Rackwitz; Juliusz A Wolny; Kai Schlage; Hans-Christian Wille; Aleksandr Chumakov; Sergiy Krasutsky; Philippe Chaignon; C Dale Poulter; Myriam Seemann; Volker Schünemann
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-26       Impact factor: 15.336

3.  Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non-diphosphate Inhibitors.

Authors:  Bing O'Dowd; Sarah Williams; Hongxin Wang; Joo Hwan No; Guodong Rao; Weixue Wang; J Andrew McCammon; Stephen P Cramer; Eric Oldfield
Journal:  Chembiochem       Date:  2017-04-07       Impact factor: 3.164

4.  Inhibition of the 4Fe-4S Proteins IspG and IspH: an EPR, ENDOR and HYSCORE Investigation.

Authors:  Francisco Guerra; Ke Wang; Jikun Li; Weixue Wang; Yi-Liang Liu; Shivani Amin; Eric Oldfield
Journal:  Chem Sci       Date:  2014-04-01       Impact factor: 9.825

5.  Broken-Symmetry DFT Computations for the Reaction Pathway of IspH, an Iron-Sulfur Enzyme in Pathogenic Bacteria.

Authors:  Patrick G Blachly; Gregory M Sandala; Debra Ann Giammona; Donald Bashford; J Andrew McCammon; Louis Noodleman
Journal:  Inorg Chem       Date:  2015-06-22       Impact factor: 5.165

Review 6.  The Reductive Dehydroxylation Catalyzed by IspH, a Source of Inspiration for the Development of Novel Anti-Infectives.

Authors:  Hannah Jobelius; Gabriella Ines Bianchino; Franck Borel; Philippe Chaignon; Myriam Seemann
Journal:  Molecules       Date:  2022-01-21       Impact factor: 4.411

7.  Utilizing a dynamical description of IspH to aid in the development of novel antimicrobial drugs.

Authors:  Patrick G Blachly; César A F de Oliveira; Sarah L Williams; J Andrew McCammon
Journal:  PLoS Comput Biol       Date:  2013-12-19       Impact factor: 4.475

8.  Insights into the binding of pyridines to the iron-sulfur enzyme IspH.

Authors:  Ingrid Span; Ke Wang; Wolfgang Eisenreich; Adelbert Bacher; Yong Zhang; Eric Oldfield; Michael Groll
Journal:  J Am Chem Soc       Date:  2014-05-22       Impact factor: 15.419

Review 9.  New Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in Plasmodium.

Authors:  Gagandeep S Saggu; Zarna R Pala; Shilpi Garg; Vishal Saxena
Journal:  Front Microbiol       Date:  2016-09-13       Impact factor: 5.640
  9 in total

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