Literature DB >> 23297033

RamiGO: an R/Bioconductor package providing an AmiGO visualize interface.

Markus S Schröder1, Daniel Gusenleitner, John Quackenbush, Aedín C Culhane, Benjamin Haibe-Kains.   

Abstract

SUMMARY: The R/Bioconductor package RamiGO is an R interface to AmiGO that enables visualization of Gene Ontology (GO) trees. Given a list of GO terms, RamiGO uses the AmiGO visualize API to import Graphviz-DOT format files into R, and export these either as images (SVG, PNG) or into Cytoscape for extended network analyses. RamiGO provides easy customization of annotation, highlighting of specific GO terms, colouring of terms by P-value or export of a simplified summary GO tree. We illustrate RamiGO functionalities in a genome-wide gene set analysis of prognostic genes in breast cancer.
AVAILABILITY AND IMPLEMENTATION: RamiGO is provided in R/Bioconductor, is open source under the Artistic-2.0 License and is available with a user manual containing installation, operating instructions and tutorials. It requires R version 2.15.0 or higher. URL: http://bioconductor.org/packages/release/bioc/html/RamiGO.html

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Year:  2013        PMID: 23297033      PMCID: PMC3582261          DOI: 10.1093/bioinformatics/bts708

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  6 in total

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  6 in total
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