Literature DB >> 23293115

Relevance of a systematic geriatric screening and assessment in older patients with cancer: results of a prospective multicentric study.

C Kenis1, D Bron, Y Libert, L Decoster, K Van Puyvelde, P Scalliet, P Cornette, T Pepersack, S Luce, C Langenaeken, M Rasschaert, S Allepaerts, R Van Rijswijk, K Milisen, J Flamaing, J-P Lobelle, H Wildiers.   

Abstract

BACKGROUND: To evaluate the large-scale feasibility and usefulness of geriatric screening and assessment in clinical oncology practice by assessing the impact on the detection of unknown geriatric problems, geriatric interventions and treatment decisions. PATIENTS AND METHODS: Eligible patients who had a malignant tumour were ≥70 years old and treatment decision had to be made. Patients were screened using G8; if abnormal (score ≤14/17) followed by Comprehensive Geriatric Assessment (CGA). The assessment results were communicated to the treating physician using a predefined questionnaire to assess the topics mentioned above.
RESULTS: One thousand nine hundred and sixty-seven patients were included in 10 hospitals. Of these patients, 70.7% had an abnormal G8 score warranting a CGA. Physicians were aware of the assessment results at the time of treatment decision in two-thirds of the patients (n = 1115; 61.3%). The assessment detected unknown geriatric problems in 51.2% of patients. When the physician was aware of the assessment results at the time of decision making, geriatric interventions were planned in 286 patients (25.7%) and the treatment decision was influenced in 282 patients (25.3%).
CONCLUSION: Geriatric screening and assessment in older patients with cancer is feasible at large scale and has a significant impact on the detection of unknown geriatric problems, leading to geriatric interventions and adapted treatment.

Entities:  

Mesh:

Year:  2013        PMID: 23293115     DOI: 10.1093/annonc/mds619

Source DB:  PubMed          Journal:  Ann Oncol        ISSN: 0923-7534            Impact factor:   32.976


  66 in total

1.  Geriatric Assessment and Functional Decline in Older Patients with Lung Cancer.

Authors:  L Decoster; C Kenis; D Schallier; J Vansteenkiste; K Nackaerts; L Vanacker; N Vandewalle; J Flamaing; J P Lobelle; K Milisen; J De Grève; H Wildiers
Journal:  Lung       Date:  2017-06-20       Impact factor: 2.584

2.  Geriatric Assessment for Older Patients with Non-small Cell Lung Cancer: Daily Practice of Centers Participating in the NVALT25-ELDAPT Trial.

Authors:  Elisabeth J M Driessen; Judith G M van Loon; Huub A Maas; Anne-Marie C Dingemans; Maryska L G Janssen-Heijnen
Journal:  Lung       Date:  2018-04-12       Impact factor: 2.584

3.  Association between patient-reported hearing and visual impairments and functional, psychological, and cognitive status among older adults with cancer.

Authors:  Enrique Soto-Perez-de-Celis; Can-Lan Sun; William P Tew; Supriya Gupta Mohile; Ajeet Gajra; Heidi D Klepin; Cynthia Owusu; Cary Philip Gross; Hyman B Muss; Stuart M Lichtman; Andrew E Chapman; Harvey Jay Cohen; William Dale; Heeyoung Kim; Simone Fernandes; Vani Katheria; Arti Hurria
Journal:  Cancer       Date:  2018-05-24       Impact factor: 6.860

Review 4.  Assessing MGMT methylation status and its current impact on treatment in glioblastoma.

Authors:  Anna S Berghoff; Johannes A Hainfellner; Christine Marosi; Matthias Preusser
Journal:  CNS Oncol       Date:  2015

5.  Geriatric Assessment of Older Adults With Cancer During Unplanned Hospitalizations: An Opportunity in Disguise.

Authors:  Caroline Mariano; Grant Williams; Allison Deal; Shani Alston; Ashley Leak Bryant; Trevor Jolly; Hyman B Muss
Journal:  Oncologist       Date:  2015-06-01

6.  Changes in the Use of Comprehensive Geriatric Assessment in Clinical Trials for Older Patients with Cancer over Time.

Authors:  Olivia Le Saux; Claire Falandry; Hui K Gan; Benoit You; Gilles Freyer; Julien Péron
Journal:  Oncologist       Date:  2019-02-01

7.  Geriatric Assessment Predicts Survival and Competing Mortality in Elderly Patients with Early Colorectal Cancer: Can It Help in Adjuvant Therapy Decision-Making?

Authors:  Maite Antonio; Juana Saldaña; Alberto Carmona-Bayonas; Valentín Navarro; Cristian Tebé; Marga Nadal; Francesc Formiga; Ramon Salazar; Josep Maria Borràs
Journal:  Oncologist       Date:  2017-05-09

8.  Expert consensus panel guidelines on geriatric assessment in oncology.

Authors:  A O'Donovan; S G Mohile; M Leech
Journal:  Eur J Cancer Care (Engl)       Date:  2015-03-11       Impact factor: 2.520

9.  Utility of a chemotherapy toxicity prediction tool for older patients in a community setting.

Authors:  C Mariano; R Jamal; P Bains; S Hejazi; L Chao; J Wan; J Ho
Journal:  Curr Oncol       Date:  2019-08-01       Impact factor: 3.677

Review 10.  Systemic Treatment for Older Patients with Unresectable Hepatocellular Carcinoma.

Authors:  Antonella Cammarota; Antonio D'Alessio; Tiziana Pressiani; Lorenza Rimassa; Nicola Personeni
Journal:  Drugs Aging       Date:  2021-06-21       Impact factor: 3.923

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