Literature DB >> 23292033

Pediatric clinical pharmacology: an introduction to a series of educational papers.

Karel Allegaert1.   

Abstract

Drug therapy is a very powerful tool to improve the medical outcome of children. Despite this fact, pediatricians still commonly prescribe drug formulations that were developed for adults. In this series of educational papers related to pediatric clinical pharmacology, we aim to raise awareness on different aspects of clinical pharmacology in children, covering neonatal clinical pharmacology, formulation-related issues, ethical aspects of clinical research, pharmacovigilance, and training in pediatric clinical pharmacology. We want to illustrate the relevance of this re-emerging research field for the practicing clinician, although we are very much aware that these topics do not fully cover the multifaceted landscape of pediatric clinical pharmacology. We hope that many readers will reconsider their daily clinical practices and will be stimulated to collaborate to further improve pediatric drug therapy throughout Europe and beyond.

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Year:  2013        PMID: 23292033     DOI: 10.1007/s00431-012-1921-3

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  20 in total

1.  Design of a pediatric oral formulation with a low proportion of hydrochlorothiazide.

Authors:  A Santoveña; Z Hernández-Paiz; J B Fariña
Journal:  Int J Pharm       Date:  2011-12-01       Impact factor: 5.875

2.  Enrollment of extremely low birth weight infants in a clinical research study may not be representative.

Authors:  Wade Rich; Neil N Finer; Marie G Gantz; Nancy S Newman; Angelita M Hensman; Ellen C Hale; Kathy J Auten; Kurt Schibler; Roger G Faix; Abbot R Laptook; Bradley A Yoder; Abhik Das; Seetha Shankaran
Journal:  Pediatrics       Date:  2012-02-27       Impact factor: 7.124

3.  'Formulating better medicines for children' - still paving the road.

Authors:  Catherine Tuleu
Journal:  Int J Pharm       Date:  2012-05-21       Impact factor: 5.875

4.  The propylene glycol research project to illustrate the feasibility and difficulties to study toxicokinetics in neonates.

Authors:  Aida Kulo; Jan N de Hoon; Karel Allegaert
Journal:  Int J Pharm       Date:  2012-05-26       Impact factor: 5.875

5.  What the paediatricians need--the launch of paediatric research in Europe.

Authors:  José Ramet
Journal:  Eur J Pediatr       Date:  2005-02-22       Impact factor: 3.183

Review 6.  Developmentally informed pharmacotherapy for child and adolescent depressive disorders.

Authors:  Dara Sakolsky; Boris Birmaher
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2012-02-24

Review 7.  The role of population PK-PD modelling in paediatric clinical research.

Authors:  Roosmarijn F W De Cock; Chiara Piana; Elke H J Krekels; Meindert Danhof; Karel Allegaert; Catherijne A J Knibbe
Journal:  Eur J Clin Pharmacol       Date:  2010-03-26       Impact factor: 2.953

Review 8.  Educational paper: formulation-related issues in pediatric clinical pharmacology.

Authors:  Catherine Tuleu; Joerg Breitkreutz
Journal:  Eur J Pediatr       Date:  2012-10-31       Impact factor: 3.183

Review 9.  Clinical pharmacology in the adolescent oncology patient.

Authors:  Gareth J Veal; Christine M Hartford; Clinton F Stewart
Journal:  J Clin Oncol       Date:  2010-05-03       Impact factor: 44.544

10.  Individualized dosing regimens in children based on population PKPD modelling: are we ready for it?

Authors:  Catherijne A J Knibbe; Meindert Danhof
Journal:  Int J Pharm       Date:  2011-03-03       Impact factor: 5.875

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