Literature DB >> 23287465

Linking JNK-STAT3-Akt signaling axis to EZH2 phosphorylation: a novel pathway of carcinogenesis.

Yon Rojanasakul1.   

Abstract

Entities:  

Keywords:  EZH2; JNK; arsenic; cancer stem cells; carcinogenesis

Mesh：

Substances：

Year:  2012        PMID： 23287465      PMCID： PMC3575446          DOI： 10.4161/cc.23419

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  9 in total

1.  Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways.

Authors:  Chunmei Wang; Salvatore Delogu; Coral Ho; Susie A Lee; Bing Gui; Lijie Jiang; Sara Ladu; Antonio Cigliano; Frank Dombrowski; Matthias Evert; Diego F Calvisi; Xin Chen
Journal:  J Hepatol       Date:  2012-05-19       Impact factor: 25.083

2.  Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3.

Authors:  Tai-Lung Cha; Binhua P Zhou; Weiya Xia; Yadi Wu; Cheng-Chieh Yang; Chun-Te Chen; Bo Ping; Arie P Otte; Mien-Chie Hung
Journal:  Science       Date:  2005-10-14       Impact factor: 47.728

Review 3.  JNK-induced apoptosis, compensatory growth, and cancer stem cells.

Authors:  Fei Chen
Journal:  Cancer Res       Date:  2012-01-15       Impact factor: 12.701

4.  JNK-dependent Stat3 phosphorylation contributes to Akt activation in response to arsenic exposure.

Authors:  Jia Liu; Bailing Chen; Yongju Lu; Youfei Guan; Fei Chen
Journal:  Toxicol Sci       Date:  2012-06-13       Impact factor: 4.849

5.  SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis.

Authors:  Meiling Gao; Rachana Patel; Imran Ahmad; Janis Fleming; Joanne Edwards; Stuart McCracken; Kanagasabai Sahadevan; Morag Seywright; Jim Norman; Owen Sansom; Hing Y Leung
Journal:  EMBO Mol Med       Date:  2012-05-31       Impact factor: 12.137

6.  JNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenic.

Authors:  Bailing Chen; Jia Liu; Qingshan Chang; Kevin Beezhold; Yongju Lu; Fei Chen
Journal:  Cell Cycle       Date:  2012-12-19       Impact factor: 4.534

7.  Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells.

Authors:  Yuanji Lin; Ying Yang; Weihua Li; Qi Chen; Jie Li; Xiao Pan; Lina Zhou; Changwei Liu; Chunsong Chen; Jianqin He; Hongcui Cao; Hangping Yao; Li Zheng; Xiaowei Xu; Zongping Xia; Jiangtao Ren; Lei Xiao; Lanjuan Li; Binghui Shen; Honglin Zhou; Ying-Jie Wang
Journal:  Mol Cell       Date:  2012-10-04       Impact factor: 17.970

8.  Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation.

Authors:  Lijian Hui; Kurt Zatloukal; Harald Scheuch; Ewa Stepniak; Erwin F Wagner
Journal:  J Clin Invest       Date:  2008-11-06       Impact factor: 14.808

Review 9.  The role of EZH2 in tumour progression.

Authors:  C-J Chang; M-C Hung
Journal:  Br J Cancer       Date:  2011-12-20       Impact factor: 7.640
  9 in total
  9 in total

Review 1.  Regulation and role of post-translational modifications of enhancer of zeste homologue 2 in cancer development.

Authors:  Haiqi Lu; Guangliang Li; Chenyi Zhou; Wei Jin; Xiaoling Qian; Zhuo Wang; Hongming Pan; Hongchuan Jin; Xian Wang
Journal:  Am J Cancer Res       Date:  2016-12-01       Impact factor: 6.166

2.  Androgens Regulate Ovarian Gene Expression Through Modulation of Ezh2 Expression and Activity.

Authors:  Xiaoting Ma; Emily Hayes; Anindita Biswas; Christina Seger; Hen Prizant; Stephen R Hammes; Aritro Sen
Journal:  Endocrinology       Date:  2017-09-01       Impact factor: 4.736

3.  Carcinogenic metalloid arsenic induces expression of mdig oncogene through JNK and STAT3 activation.

Authors:  Jiaying Sun; Miaomiao Yu; Yongju Lu; Chitra Thakur; Bailing Chen; Ping Qiu; Hongwen Zhao; Fei Chen
Journal:  Cancer Lett       Date:  2014-01-14       Impact factor: 8.679

Review 4.  Androgen-induced epigenetic modulations in the ovary.

Authors:  Irving Salinas; Niharika Sinha; Aritro Sen
Journal:  J Endocrinol       Date:  2021-06       Impact factor: 4.669

Review 5.  Epigenetic Dysregulation at the Crossroad of Women's Cancer.

Authors:  Rakesh Kumar; Aswathy Mary Paul; Pranela Rameshwar; M Radhakrishna Pillai
Journal:  Cancers (Basel)       Date:  2019-08-16       Impact factor: 6.639

Review 6.  The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials.

Authors:  Seidu A Richard; Kuugbee D Eugene
Journal:  Anal Cell Pathol (Amst)       Date:  2021-10-27       Impact factor: 2.916

7.  STAT3/miR-130b-3p/MBNL1 feedback loop regulated by mTORC1 signaling promotes angiogenesis and tumor growth.

Authors:  Hongwu Li; Ping Liu; Dapeng Li; Zixi Wang; Zhao Ding; Meng Zhou; Xu Chen; Manli Miao; Junli Ding; Wei Lin; Yehai Liu; Xiaojun Zha
Journal:  J Exp Clin Cancer Res       Date:  2022-10-11

8.  Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells.

Authors:  Kai Wu; Qingshan Chang; Yongju Lu; Ping Qiu; Bailing Chen; Chitra Thakur; Jiaying Sun; Lingzhi Li; Anjaneyulu Kowluru; Fei Chen
Journal:  Oncotarget       Date:  2013-12

9.  MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer.

Authors:  Beiqin Yu; Xin Lv; Liping Su; Jianfang Li; Yingyan Yu; Qinlong Gu; Min Yan; Zhenggang Zhu; Bingya Liu
Journal:  PLoS One       Date:  2016-08-12       Impact factor: 3.240
  9 in total

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