Literature DB >> 22253282

JNK-induced apoptosis, compensatory growth, and cancer stem cells.

Fei Chen1.   

Abstract

Overwhelming are a set of key stress-responsive kinases that mediate cell apoptosis, which is an important process for tumor suppression. However, JNKs have also been implicated in the malignant transformation and tumorigenesis of cells. This review attempts to reconcile these 2 contradictory functions of JNKs with recent discoveries on the role of JNKs in compensatory growth of neighboring cells and stem cells, which may provide new mechanistic understanding about the role of JNKs in the regulation of cancer stem cells and the pathogenesis of cancers.

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Year:  2012        PMID： 22253282      PMCID： PMC3261582          DOI： 10.1158/0008-5472.CAN-11-1982

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  104 in total

1.  Profiling of differentially expressed genes in human stem cells by cDNA microarray.

Authors:  Chul Geun Kim; Jong Joo Lee; Dae Young Jung; Jinseon Jeon; Hyen Seok Heo; Ho Chul Kang; June Ho Shin; Yoon Shin Cho; Kyung Joon Cha; Chan Gil Kim; Byung-Rok Do; Kyung Suk Kim; Hyun-Soo Kim
Journal:  Mol Cells       Date:  2006-06-30       Impact factor: 5.034

2.  The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

Authors:  Lyle Armstrong; Owen Hughes; Sun Yung; Louise Hyslop; Rebecca Stewart; Ilka Wappler; Heiko Peters; Theresia Walter; Petra Stojkovic; Jerome Evans; Miodrag Stojkovic; Majlinda Lako
Journal:  Hum Mol Genet       Date:  2006-04-27       Impact factor: 6.150

Review 3.  Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.

Authors:  Marie A Bogoyevitch; Bostjan Kobe
Journal:  Microbiol Mol Biol Rev       Date:  2006-12       Impact factor: 11.056

4.  Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation.

Authors:  Toshiharu Sakurai; Shin Maeda; Lufen Chang; Michael Karin
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-28       Impact factor: 11.205

Review 5.  Wnt/beta-catenin signaling in cancer stemness and malignant behavior.

Authors:  Riccardo Fodde; Thomas Brabletz
Journal:  Curr Opin Cell Biol       Date:  2007-02-16       Impact factor: 8.382

6.  Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion.

Authors:  Hsin-Sheng Yang; Connie P Matthews; Timothy Clair; Qing Wang; Alyson R Baker; Chou-Chi H Li; Tse-Hua Tan; Nancy H Colburn
Journal:  Mol Cell Biol       Date:  2006-02       Impact factor: 4.272

7.  Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma.

Authors:  Tom Luedde; Naiara Beraza; Vasileios Kotsikoris; Geert van Loo; Arianna Nenci; Rita De Vos; Tania Roskams; Christian Trautwein; Manolis Pasparakis
Journal:  Cancer Cell       Date:  2007-02       Impact factor: 31.743

Review 8.  Wiring the cell signaling circuitry by the NF-kappa B and JNK1 crosstalk and its applications in human diseases.

Authors:  J Liu; A Lin
Journal:  Oncogene       Date:  2007-05-14       Impact factor: 9.867

9.  Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production.

Authors:  Willscott E Naugler; Toshiharu Sakurai; Sunhwa Kim; Shin Maeda; Kyounghyun Kim; Ahmed M Elsharkawy; Michael Karin
Journal:  Science       Date:  2007-07-06       Impact factor: 47.728

Review 10.  The functional contrariety of JNK.

Authors:  Ann M Bode; Zigang Dong
Journal:  Mol Carcinog       Date:  2007-08       Impact factor: 4.784
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  87 in total

1.  JNK signalling is necessary for a Wnt- and stem cell-dependent regeneration programme.

Authors:  Belen Tejada-Romero; Jean-Michel Carter; Yuliana Mihaylova; Bjoern Neumann; A Aziz Aboobaker
Journal:  Development       Date:  2015-06-10       Impact factor: 6.868

2.  Knockdown of eukaryotic translation initiation factor 3 subunit D (eIF3D) inhibits proliferation of acute myeloid leukemia cells.

Authors:  Guo-Zhen Liu; Ji-Zhu Liu; Xiao-Qing Li; Li Zhang; Shuang-Jing Li; Tai-Wu Xiao; Jing-Xia Wang; Guang-Yao Li; Yusen Liu
Journal:  Mol Cell Biochem       Date:  2017-08-12       Impact factor: 3.396

Review 3.  Nitrosothiol signaling and protein nitrosation in cell death.

Authors:  Anand Krishnan V Iyer; Yon Rojanasakul; Neelam Azad
Journal:  Nitric Oxide       Date:  2014-07-23       Impact factor: 4.427

4.  The involvement of the mGluR5-mediated JNK signaling pathway in rats with diabetic retinopathy.

Authors:  Yan-Ni Zhu; Guo-Jin Zuo; Qi Wang; Xiao-Ming Chen; Jin-Kui Cheng; Shu Zhang
Journal:  Int Ophthalmol       Date:  2019-01-03       Impact factor: 2.031

Review 5.  Cell motility in cancer invasion and metastasis: insights from simple model organisms.

Authors:  Christina H Stuelten; Carole A Parent; Denise J Montell
Journal:  Nat Rev Cancer       Date:  2018-03-16       Impact factor: 60.716

6.  c-Jun promotes the survival of H9c2 cells under hypoxia via PTEN/Akt signaling pathway.

Authors:  Fan Wu; Feng Gao; Siyi He; Yunhan Jiang; Guiping Luo; Yingbin Xiao
Journal:  J Physiol Biochem       Date:  2019-08-03       Impact factor: 4.158

7.  JNK and STAT3 signaling pathways converge on Akt-mediated phosphorylation of EZH2 in bronchial epithelial cells induced by arsenic.

Authors:  Bailing Chen; Jia Liu; Qingshan Chang; Kevin Beezhold; Yongju Lu; Fei Chen
Journal:  Cell Cycle       Date:  2012-12-19       Impact factor: 4.534

Review 8.  Eph receptor tyrosine kinases in cancer stem cells.

Authors:  Jin Chen; Wenqiang Song; Katherine Amato
Journal:  Cytokine Growth Factor Rev       Date:  2014-05-17       Impact factor: 7.638

9.  c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun.

Authors:  X Xie; T S Kaoud; R Edupuganti; T Zhang; T Kogawa; Y Zhao; G B Chauhan; D N Giannoukos; Y Qi; D Tripathy; J Wang; N S Gray; K N Dalby; C Bartholomeusz; N T Ueno
Journal:  Oncogene       Date:  2016-12-12       Impact factor: 9.867

10.  E4orf4 induces PP2A- and Src-dependent cell death in Drosophila melanogaster and at the same time inhibits classic apoptosis pathways.

Authors:  Antonina Pechkovsky; Maoz Lahav; Eliya Bitman; Adi Salzberg; Tamar Kleinberger
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-23       Impact factor: 11.205
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