Literature DB >> 23283851

Small-molecule lipid-bilayer anion transporters for biological applications.

Nathalie Busschaert1, Philip A Gale.   

Abstract

The development of small-molecule lipid-bilayer anion transporters for potential future use in channel replacement therapy for the treatment of diseases caused by dysregulation of anion transport (such as cystic fibrosis), and in treating cancer by perturbing chemical gradients within cells, thus triggering apoptosis, is an area of intense current interest. This Minireview looks at recent developments in the design of small-molecule transmembrane anion transporters and focuses on the progress so far in employing these compounds in biological systems.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23283851     DOI： 10.1002/anie.201207535

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  17 in total

1.  Efficient, non-toxic anion transport by synthetic carriers in cells and epithelia.

Authors:  Hongyu Li; Hennie Valkenier; Luke W Judd; Peter R Brotherhood; Sabir Hussain; James A Cooper; Ondřej Jurček; Hazel A Sparkes; David N Sheppard; Anthony P Davis
Journal:  Nat Chem       Date:  2015-11-02       Impact factor: 24.427

2.  Ion transport: Tipping a cell's ionic balance.

Authors:  Jeffery T Davis
Journal:  Nat Chem       Date:  2014-10       Impact factor: 24.427

3.  Pyrrole N-H Anion Complexes.

Authors:  Gabriela I Vargas-Zúñiga; Jonathan L Sessler
Journal:  Coord Chem Rev       Date:  2017-04-20       Impact factor: 22.315

4.  Thiosquaramides: pH switchable anion transporters.

Authors:  Nathalie Busschaert; Robert B P Elmes; Dawid D Czech; Xin Wu; Isabelle L Kirby; Evan M Peck; Kevin D Hendzel; Scott K Shaw; Bun Chan; Bradley D Smith; Katrina A Jolliffe; Philip A Gale
Journal:  Chem Sci       Date:  2014-09-01       Impact factor: 9.825

5.  Restored Physiology in Protein-Deficient Yeast by a Small Molecule Channel.

Authors:  Alexander G Cioffi; Jennifer Hou; Anthony S Grillo; Katrina A Diaz; Martin D Burke
Journal:  J Am Chem Soc       Date:  2015-08-07       Impact factor: 15.419

6.  Chloride anion transporters inhibit growth of methicillin-resistant Staphylococcus aureus (MRSA) in vitro.

Authors:  Andrew I Share; Khushali Patel; Cristina Nativi; Eun J Cho; Oscar Francesconi; Nathalie Busschaert; Philip A Gale; Stefano Roelens; Jonathan L Sessler
Journal:  Chem Commun (Camb)       Date:  2016-05-25       Impact factor: 6.222

7.  Visualization and quantification of transmembrane ion transport into giant unilamellar vesicles.

Authors:  Hennie Valkenier; Néstor López Mora; Alexander Kros; Anthony P Davis
Journal:  Angew Chem Int Ed Engl       Date:  2014-12-30       Impact factor: 15.336

8.  Small molecule anionophores promote transmembrane anion permeation matching CFTR activity.

Authors:  Elsa Hernando; Valeria Capurro; Claudia Cossu; Michele Fiore; María García-Valverde; Vanessa Soto-Cerrato; Ricardo Pérez-Tomás; Oscar Moran; Olga Zegarra-Moran; Roberto Quesada
Journal:  Sci Rep       Date:  2018-02-08       Impact factor: 4.379

9.  Prodigiosin analogue designed for metal coordination: stable zinc and copper pyrrolyldipyrrins.

Authors:  Tsuhen M Chang; Sanhita Sinharay; Andrei V Astashkin; Elisa Tomat
Journal:  Inorg Chem       Date:  2014-07-10       Impact factor: 5.165

Review 10.  Anion Recognition in Water: Recent Advances from a Supramolecular and Macromolecular Perspective.

Authors:  Matthew J Langton; Christopher J Serpell; Paul D Beer
Journal:  Angew Chem Int Ed Engl       Date:  2015-11-27       Impact factor: 15.336
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