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Literature DB >> 23280953

Small-molecule-mediated cleavage of RNA in living cells.

Lirui Guan¹, Matthew D Disney.

Abstract

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 23280953 PMCID： PMC3711026 DOI： 10.1002/anie.201206888

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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26 in total

Review 1. Progress in antisense technology.

Authors: Stanley T Crooke
Journal: Annu Rev Med Date: 2004 Impact factor: 13.739

2. Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells.

Authors: L F Johnson; J G Williams; H T Abelson; H Green; S Penman
Journal: Cell Date: 1975-01 Impact factor: 41.582

Review 3. Riboswitches as antibacterial drug targets.

Authors: Kenneth F Blount; Ronald R Breaker
Journal: Nat Biotechnol Date: 2006-12 Impact factor: 54.908

4. A small molecule microarray platform to select RNA internal loop-ligand interactions.

Authors: Jessica L Childs-Disney; Meilan Wu; Alexei Pushechnikov; Olga Aminova; Matthew D Disney
Journal: ACS Chem Biol Date: 2007-11-02 Impact factor: 5.100

5. Antibacterial lysine analogs that target lysine riboswitches.

Authors: Kenneth F Blount; Joy Xin Wang; Jinsoo Lim; Narasimhan Sudarsan; Ronald R Breaker
Journal: Nat Chem Biol Date: 2006-12-03 Impact factor: 15.040

6. Studies of RNA cleavage by photolysis of N-hydroxypyridine-2(1H)-thione. A new photochemical footprinting method.

Authors: S G Chaulk; J P Pezacki; A M MacMillan
Journal: Biochemistry Date: 2000-08-29 Impact factor: 3.162

7. Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat.

Authors: A Mankodi; E Logigian; L Callahan; C McClain; R White; D Henderson; M Krym; C A Thornton
Journal: Science Date: 2000-09-08 Impact factor: 47.728

Review 8. RNA pathogenesis of the myotonic dystrophies.

Authors: John W Day; Laura P W Ranum
Journal: Neuromuscul Disord Date: 2004-11-26 Impact factor: 4.296

9. Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons.

Authors: Hong Jiang; Ami Mankodi; Maurice S Swanson; Richard T Moxley; Charles A Thornton
Journal: Hum Mol Genet Date: 2004-10-20 Impact factor: 6.150

10. Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure.

Authors: David H Mathews; Matthew D Disney; Jessica L Childs; Susan J Schroeder; Michael Zuker; Douglas H Turner
Journal: Proc Natl Acad Sci U S A Date: 2004-05-03 Impact factor: 11.205

16 in total

1. A Toxic RNA Templates the Synthesis of Its Own Fluorogenic Inhibitor by Using a Bio-orthogonal Tetrazine Ligation in Cells and Tissues.

Authors: Alicia J Angelbello; Matthew D Disney
Journal: ACS Chem Biol Date: 2020-06-17 Impact factor: 5.100

2. Identifying and validating small molecules interacting with RNA (SMIRNAs).

Authors: Matthew D Disney; Sai Pradeep Velagapudi; Yue Li; Matthew G Costales; Jessica L Childs-Disney
Journal: Methods Enzymol Date: 2019-05-15 Impact factor: 1.600

Review 3. Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA-Small Molecule Interactions.

Authors: Aline Umuhire Juru; Neeraj N Patwardhan; Amanda E Hargrove
Journal: ACS Chem Biol Date: 2019-05-01 Impact factor: 5.100

Small-molecule-mediated cleavage of RNA in living cells.

Review 1. Progress in antisense technology.

2. Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells.

Review 3. Riboswitches as antibacterial drug targets.

4. A small molecule microarray platform to select RNA internal loop-ligand interactions.

5. Antibacterial lysine analogs that target lysine riboswitches.

6. Studies of RNA cleavage by photolysis of N-hydroxypyridine-2(1H)-thione. A new photochemical footprinting method.

7. Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat.

Review 8. RNA pathogenesis of the myotonic dystrophies.

9. Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons.

10. Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure.

1. A Toxic RNA Templates the Synthesis of Its Own Fluorogenic Inhibitor by Using a Bio-orthogonal Tetrazine Ligation in Cells and Tissues.

2. Identifying and validating small molecules interacting with RNA (SMIRNAs).

Review 3. Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA-Small Molecule Interactions.

4. Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms.

Review 5. Approaches to Validate and Manipulate RNA Targets with Small Molecules in Cells.

Review 6. Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.

7. Rational Design of Small Molecules Targeting Oncogenic Noncoding RNAs from Sequence.

8. Covalent small-molecule-RNA complex formation enables cellular profiling of small-molecule-RNA interactions.

9. Precise Targeted Cleavage of a r(CUG) Repeat Expansion in Cells by Using a Small-Molecule-Deglycobleomycin Conjugate.

10. Small molecule alteration of RNA sequence in cells and animals.