| Literature DB >> 23277280 |
Abstract
Why stem cell numbers decline with age is a major question in regenerative biology and medicine. Skeletal muscle has emerged as a powerful paradigm to address this issue. Recently, genetic and cell marking strategies were used to uncover a new and causal relationship between muscle stem cells and differentiated fibers that constitute their niche and provoke their loss.Mesh:
Year: 2013 PMID: 23277280 PMCID: PMC3616425 DOI: 10.1038/cr.2013.3
Source DB: PubMed Journal: Cell Res ISSN: 1001-0602 Impact factor: 25.617