Literature DB >> 23273900

A multicentre observational study of the outcomes of screening detected sub-aneurysmal aortic dilatation.

J B Wild1, P W Stather, F Biancari, E C Choke, J J Earnshaw, S W Grant, H Hafez, R Holdsworth, T Juvonen, J Lindholt, C McCollum, S Parvin, R D Sayers, M J Bown.   

Abstract

OBJECTIVES: Currently most abdominal aortic aneurysm screening programmes discharge patients with aortic diameter of less than 30 mm. However, sub-aneurysmal aortic dilatation (25 mm-29 mm) does not represent a normal aortic diameter. This observational study aimed to determine the outcomes of patients with screening detected sub aneurysmal aortic dilatation. DESIGN AND METHODS: Individual patient data was obtained from 8 screening programmes that had performed long term follow up of patients with sub aneurysmal aortic dilatation. Outcome measures recorded were the progression to true aneurysmal dilatation (aortic diameter 30 mm or greater), progression to size threshold for surgical intervention (55 mm) and aneurysm rupture.
RESULTS: Aortic measurements for 1696 men and women (median age 66 years at initial scan) with sub-aneurysmal aortae were obtained, median period of follow up was 4.0 years (range 0.1-19.0 years). Following Kaplan Meier and life table analysis 67.7% of patients with 5 complete years of surveillance reached an aortic diameter of 30 mm or greater however 0.9% had an aortic diameter of 54 mm. A total of 26.2% of patients with 10 complete years of follow up had an AAA of greater that 54 mm.
CONCLUSION: Patients with sub-aneurysmal aortic dilatation are likely to progress and develop an AAA, although few will rupture or require surgical intervention.
Copyright © 2012 European Society for Vascular Surgery. All rights reserved.

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Year:  2012        PMID: 23273900     DOI: 10.1016/j.ejvs.2012.11.024

Source DB:  PubMed          Journal:  Eur J Vasc Endovasc Surg        ISSN: 1078-5884            Impact factor:   7.069


  10 in total

1.  Risk of developing an abdominal aortic aneurysm after ectatic aorta detection from initial screening.

Authors:  Kevin C Chun; Richard C Anderson; Hunter C Smothers; Kanika Sood; Zachary T Irwin; Machelle D Wilson; Eugene S Lee
Journal:  J Vasc Surg       Date:  2019-11-07       Impact factor: 4.268

2.  Prognostic value of D-dimer and markers of coagulation for stratification of abdominal aortic aneurysm growth.

Authors:  Alexandra C Sundermann; Keith Saum; Kelsey A Conrad; Hannah M Russell; Todd L Edwards; Kevin Mani; Martin Björck; Anders Wanhainen; A Phillip Owens
Journal:  Blood Adv       Date:  2018-11-27

3.  Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice.

Authors:  Xiao-Fang Huang; Song-Zhao Zhang; Ya-Yu You; Na Zhang; Hong Lu; Alan Daugherty; Xiao-Jie Xie
Journal:  Acta Pharmacol Sin       Date:  2018-05-18       Impact factor: 6.150

Review 4.  Ruptured abdominal aortic aneurysm-epidemiology, predisposing factors, and biology.

Authors:  Thomas Schmitz-Rixen; M Keese; M Hakimi; A Peters; D Böckler; K Nelson; R T Grundmann
Journal:  Langenbecks Arch Surg       Date:  2016-03-21       Impact factor: 3.445

5.  Early Detection of Undiagnosed Abdominal Aortic Aneurysm and Sub-Aneurysmal Aortic Dilatations in Patients with High-Risk Coronary Artery Disease: The Value of Targetted Screening Programme.

Authors:  Siong Teng Saw; Benjamin Dak Keung Leong; Dayang Anita Abdul Aziz
Journal:  Vasc Health Risk Manag       Date:  2020-06-09

Review 6.  Prevalence and natural history of and risk factors for subaneurysmal aorta among 65-year-old men.

Authors:  Knut Thorbjørnsen; Sverker Svensjö; Khatereh Djavani Gidlund; Nils-Peter Gilgen; Anders Wanhainen
Journal:  Ups J Med Sci       Date:  2019-08-28       Impact factor: 2.384

7.  Abdominal Aortic Screening Is a Priority for Health in Smoker Males: A Study on Central Italian Population.

Authors:  Emma Altobelli; Filippo Gianfelice; Paolo Matteo Angeletti; Reimondo Petrocelli
Journal:  Int J Environ Res Public Health       Date:  2022-01-05       Impact factor: 3.390

8.  Prehabilitation exercise therapy before elective abdominal aortic aneurysm repair.

Authors:  Candida Fenton; Audrey R Tan; Ukachukwu Okoroafor Abaraogu; James E McCaslin
Journal:  Cochrane Database Syst Rev       Date:  2021-07-08

9.  Discrete Event Simulation for Decision Modeling in Health Care: Lessons from Abdominal Aortic Aneurysm Screening.

Authors:  Matthew J Glover; Edmund Jones; Katya L Masconi; Michael J Sweeting; Simon G Thompson
Journal:  Med Decis Making       Date:  2018-04-02       Impact factor: 2.583

Review 10.  AAA Revisited: A Comprehensive Review of Risk Factors, Management, and Hallmarks of Pathogenesis.

Authors:  Veronika Kessler; Johannes Klopf; Wolf Eilenberg; Christoph Neumayer; Christine Brostjan
Journal:  Biomedicines       Date:  2022-01-02
  10 in total

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