Literature DB >> 23273894

The longevity of sirtuins.

David Sinclair1, Eric Verdin.   

Abstract

Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue of Cell Reports, Banerjee et al. demonstrate that Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.
Copyright © 2012 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 23273894     DOI： 10.1016/j.celrep.2012.12.004

Source DB:  PubMed          Journal:  Cell Rep            Impact factor:   9.423


  6 in total

1.  The many faces of sirtuins: Coupling of NAD metabolism, sirtuins and lifespan.

Authors:  Eric Verdin
Journal:  Nat Med       Date:  2014-01       Impact factor: 53.440

Review 2.  Intercellular interplay between Sirt1 signalling and cell metabolism in immune cell biology.

Authors:  Xi Chen; Yun Lu; Zhengguo Zhang; Jian Wang; Hui Yang; Guangwei Liu
Journal:  Immunology       Date:  2015-06-03       Impact factor: 7.397

3.  Coming of age: molecular drivers of aging and therapeutic opportunities.

Authors:  Christopher B Newgard; Norman E Sharpless
Journal:  J Clin Invest       Date:  2013-03-01       Impact factor: 14.808

4.  Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

Authors:  Osama Abo Alrob; Sowndramalingam Sankaralingam; Cary Ma; Cory S Wagg; Natasha Fillmore; Jagdip S Jaswal; Michael N Sack; Richard Lehner; Mahesh P Gupta; Evangelos D Michelakis; Raj S Padwal; David E Johnstone; Arya M Sharma; Gary D Lopaschuk
Journal:  Cardiovasc Res       Date:  2014-06-25       Impact factor: 10.787

Review 5.  Small-molecule allosteric activators of sirtuins.

Authors:  David A Sinclair; Leonard Guarente
Journal:  Annu Rev Pharmacol Toxicol       Date:  2013-10-16       Impact factor: 13.820

6.  Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

Authors:  Johannes Mansfeld; Nadine Urban; Steffen Priebe; Marco Groth; Christiane Frahm; Nils Hartmann; Juliane Gebauer; Meenakshi Ravichandran; Anne Dommaschk; Sebastian Schmeisser; Doreen Kuhlow; Shamci Monajembashi; Sibylle Bremer-Streck; Peter Hemmerich; Michael Kiehntopf; Nicola Zamboni; Christoph Englert; Reinhard Guthke; Christoph Kaleta; Matthias Platzer; Jürgen Sühnel; Otto W Witte; Kim Zarse; Michael Ristow
Journal:  Nat Commun       Date:  2015-12-01       Impact factor: 14.919
  6 in total

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