| Literature DB >> 23273126 |
Radwa A B Badawy1, Graeme D Jackson, Samuel F Berkovic, Richard A L Macdonell.
Abstract
Transcranial magnetic stimulation was used to study the effect of recurrent seizures on cortical excitability over time in epilepsy. 77 patients with firm diagnoses of idiopathic generalized epilepsy (IGE) or focal epilepsy were repeatedly evaluated over three years. At onset, all groups had increased cortical excitability. At the end of follow-up the refractory group was associated with a broad increase in cortical excitability. Conversely, cortical excitability decreased in all seizure free groups after introduction of an effective medication.Entities:
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Year: 2012 PMID： 23273126 DOI： 10.1142/S012906571250030X
Source DB: PubMed Journal: Int J Neural Syst ISSN： 0129-0657 Impact factor: 5.866