Literature DB >> 23271271

Early results of a modified splenic hilar lymphadenectomy in laparoscopy-assisted total gastrectomy for gastric cancer with stage cT1-2: a case-control study.

Guoxian Guan1, Weizhong Jiang, Zhifen Chen, Xing Liu, Huishan Lu, Xiangfu Zhang.   

Abstract

BACKGROUND: The aim of this study was to explore the feasibility and early outcomes of laparoscopy-assisted total gastrectomy with a modified splenic hilar lymphadenectomy for upper- and middle-third stage cT1-2 gastric cancer.
METHODS: A total of 97 patients diagnosed with upper- and middle-third stage cT1-T2 gastric cancer were enrolled. Patients were assigned to the laparoscopy-assisted total gastrectomy group (LATG, n = 41) or the open total gastrectomy group (OTG, n = 56). All patients underwent total gastrectomy with modified splenic hilar lymphadenectomy. The operative and postoperative measures, number of retrieved lymph nodes (LNs), and complications were compared between the two groups.
RESULTS: The mean number of dissected LNs was not significantly different between the two groups: 23.1 ± 8.0 in the LATG group versus 24.2 ± 7.5 in the OTG group. Compared with the OTG group, the LATG group had less operative blood loss [104.2 ± 42.9 vs. 355.6 ± 51.3 ml (p < 0.0001)], shorter time to out-of-bed activities [14.4 ± 3.2 vs. 16.5 ± 1.2 h (p < 0.0001)], shorter time to first flatus [72.2 ± 16.2 vs. 78.4 ± 8.6 h (p = 0.017)], earlier resumption of soft diet [52.8 ± 21.6 vs. 74.2 ± 12.2 h (p < 0.0001)], and shorter postoperative hospital stay [9.7 ± 2.2 vs. 13.6 ± 3.6 days (p < 0.0001)]. However, LATG had a slightly longer operating time than OTG [235.7 ± 38.5 vs. 211.5 ± 33.2 min (p = 0.001)]. The operative complications rates for the LATG and OTG groups were not significantly different: 4.9 versus 5.4 %.
CONCLUSION: For upper- and middle-third stage cT1-2 gastric cancer, a limited splenic hilar lymphadenectomy strategy seems to be safe and feasible, particularly for the number of retrieved LNs. However, this technique is not suitable for cT3 disease.

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Year:  2012        PMID: 23271271     DOI: 10.1007/s00464-012-2688-3

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  38 in total

1.  Lymph node dissection around the splenic artery and hilum in advanced middle third gastric carcinoma.

Authors:  C Li; S Kim; J F Lai; S J Oh; W J Hyung; W H Choi; S H Choi; Z G Zhu; S H Noh
Journal:  Eur J Surg Oncol       Date:  2008-05-05       Impact factor: 4.424

2.  Laparoscopy-assisted D2 radical distal gastrectomy for advanced gastric cancer.

Authors:  Jiang Long Huang; Hong Bo Wei; Zong Heng Zheng; Bo Wei; Tu Feng Chen; Yong Huang; Wei Ping Guo; Baoguang Hu
Journal:  Dig Surg       Date:  2010-07-31       Impact factor: 2.588

3.  Laparoscopic gastrectomy with regional lymph node dissection for upper gastric cancer.

Authors:  S Tanimura; M Higashino; Y Fukunaga; S Kishida; A Ogata; Y Fujiwara; H Osugi
Journal:  Br J Surg       Date:  2007-02       Impact factor: 6.939

4.  Long-term oncologic outcomes from laparoscopic gastrectomy for gastric cancer: a single-center experience of 601 consecutive resections.

Authors:  Sang-Woong Lee; Eiji Nomura; George Bouras; Takaya Tokuhara; Souichiro Tsunemi; Nobuhiko Tanigawa
Journal:  J Am Coll Surg       Date:  2010-05-26       Impact factor: 6.113

5.  Frequency of lymph node metastasis to the splenic hilus and effect of splenectomy in proximal gastric cancer.

Authors:  Shinsuke Sasada; Motoki Ninomiya; Masahiko Nishizaki; Masao Harano; Yasutomo Ojima; Hiroyoshi Matsukawa; Hideki Aoki; Shigehiro Shiozaki; Satoshi Ohno; Norohisa Takakura
Journal:  Anticancer Res       Date:  2009-08       Impact factor: 2.480

6.  Prognosis of metastatic splenic hilum lymph node in patients with gastric cancer after total gastrectomy and splenectomy.

Authors:  Keishiro Aoyagi; Kikuo Kouhuji; Motoshi Miyagi; Takuya Imaizumi; Junya Kizaki; Kazuo Shirouzu
Journal:  World J Hepatol       Date:  2010-02-27

7.  Laparoscopic pancreas- and spleen-preserving D2 lymph node dissection in advanced (cT2) upper-third gastric cancer.

Authors:  Hoon Hur; Hae Myung Jeon; Wook Kim
Journal:  J Surg Oncol       Date:  2008-02-01       Impact factor: 3.454

8.  Laparoscopically assisted total gastrectomy with lymph node dissection for upper and middle gastric cancer.

Authors:  Erito Mochiki; Yoshitaka Toyomasu; Kyouichi Ogata; Hiroyuki Andoh; Tetsuro Ohno; Ryusuke Aihara; Takayuki Asao; Hiroyuki Kuwano
Journal:  Surg Endosc       Date:  2008-07-02       Impact factor: 4.584

9.  Predictive factors for lymph node metastasis in early gastric cancer with submucosal invasion: analysis of a single institutional experience.

Authors:  Ji Yeong An; Yong Hae Baik; Min Gew Choi; Jae Hyung Noh; Tae Sung Sohn; Sung Kim
Journal:  Ann Surg       Date:  2007-11       Impact factor: 12.969

10.  A novel insight of sentinel lymph node concept based on 1-3 positive nodes in patients with pT1-2 gastric cancer.

Authors:  Baojun Huang; Zhenning Wang; Zhe Sun; Bo Zhao; Huimian Xu
Journal:  BMC Cancer       Date:  2011-01-17       Impact factor: 4.430

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  15 in total

1.  Technical aspects and short- and long-term outcomes of totally laparoscopic total gastrectomy for advanced gastric cancer: a single-institution retrospective study.

Authors:  Masaya Nakauchi; Koichi Suda; Shinichi Kadoya; Kazuki Inaba; Yoshinori Ishida; Ichiro Uyama
Journal:  Surg Endosc       Date:  2015-12-24       Impact factor: 4.584

2.  Laparoscopic versus open total gastrectomy with D2 dissection for gastric cancer: a meta-analysis.

Authors:  Weizhi Wang; Zheng Li; Jie Tang; Meilin Wang; Baolin Wang; Zekuan Xu
Journal:  J Cancer Res Clin Oncol       Date:  2013-08-30       Impact factor: 4.553

Review 3.  Laparoscopic vs open total gastrectomy for gastric cancer: a meta-analysis.

Authors:  Jun-Jie Xiong; Quentin M Nunes; Wei Huang; Chun-Lu Tan; Neng-Wen Ke; Si-Ming Xie; Xun Ran; Hao Zhang; Yong-Hua Chen; Xu-Bao Liu
Journal:  World J Gastroenterol       Date:  2013-11-28       Impact factor: 5.742

Review 4.  A systematic review of laparoscopic total gastrectomy for gastric cancer.

Authors:  Chikara Kunisaki; Hirochika Makino; Ryo Takagawa; Jun Kimura; Mitsuyoshi Ota; Yasushi Ichikawa; Takashi Kosaka; Hirotoshi Akiyama; Itaru Endo
Journal:  Gastric Cancer       Date:  2015-02-11       Impact factor: 7.370

Review 5.  Laparoscopic splenic hilar lymphadenectomy for advanced gastric cancer.

Authors:  Hisahiro Hosogi; Hiroshi Okabe; Hisashi Shinohara; Shigeru Tsunoda; Shigeo Hisamori; Yoshiharu Sakai
Journal:  Transl Gastroenterol Hepatol       Date:  2016-04-08

6.  Totally laparoscopic spleen-preserving splenic hilum lymph nodes dissection in radical total gastrectomy: an omnibearing method.

Authors:  Wei Wang; Zhiwei Liu; Wenjun Xiong; Yansheng Zheng; Lijie Luo; Dechang Diao; Jin Wan
Journal:  Surg Endosc       Date:  2015-07-23       Impact factor: 4.584

7.  Outcomes of laparoscopic versus open total gastrectomy with D2 lymphadenectomy for gastric cancer: a systematic review and meta-analysis.

Authors:  Yongpu Yang; Yuyan Chen; Yilin Hu; Ying Feng; Qinsheng Mao; Wanjiang Xue
Journal:  Eur J Med Res       Date:  2022-07-18       Impact factor: 4.981

Review 8.  Systematic review of anastomotic complications of esophagojejunostomy after laparoscopic total gastrectomy.

Authors:  Mikito Inokuchi; Sho Otsuki; Yoshitaka Fujimori; Yuya Sato; Masatoshi Nakagawa; Kazuyuki Kojima
Journal:  World J Gastroenterol       Date:  2015-08-28       Impact factor: 5.742

Review 9.  Systematic review and meta-analysis of laparoscopy-assisted and open total gastrectomy for gastric cancer.

Authors:  Ke Chen; Xiao-Wu Xu; Ren-Chao Zhang; Yu Pan; Di Wu; Yi-Ping Mou
Journal:  World J Gastroenterol       Date:  2013-08-28       Impact factor: 5.742

10.  A multi-institutional analysis of open versus minimally-invasive surgery for gastric adenocarcinoma: results of the US gastric cancer collaborative.

Authors:  Gaya Spolverato; Yuhree Kim; Aslam Ejaz; Vicente Valero; Malcolm H Squires; George Poultsides; Ryan C Fields; Mark Bloomston; Sharon M Weber; Alexandra W Acher; Konstantinos Votanopoulos; Carl Schmidt; Clifford S Cho; Shishir K Maithel; Timothy M Pawlik
Journal:  J Gastrointest Surg       Date:  2014-06-10       Impact factor: 3.452

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