Age-specific distributions of cytogenetic subgroups of acute myeloid leukemia: data analysis in a Chinese population.

Although some studies have reported relationships between cytogenetic subgroups, molecular markers and age in acute myeloid leukemia (AML), conclusions based on data from a Chinese population are lacking. In the present study, we evaluated 640 patients with de novo AML. The patients were divided into 8 age groups, i.e. 0-9, 10-19, 20-29, 30-39, 40-49, 50-59, 60-69 and ≥70 years, and were then classified into cytogenetic groups based on normal, balanced and unbalanced karyotypes.