Literature DB >> 232570

Mitogen-induced differentiation of human CLL lymphocytes to antibody-secreting cells.

K H Robèrt, A G Bird, E Möller.   

Abstract

Peripheral blood lymphocytes from nine patients with chronic lymphatic leukaemia (CLL) have been stimulated by photohaemagglutinin, pokeweed mitogen and Epstein-Barr virus. Our results provide proof that the leukaemic B cells in CLL are capable of responding to mitogenic signals by producing and secreting antibodies, transforming into blast cells, and, probably, increasing their rate of DNA synthesis.

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Year:  1979        PMID: 232570     DOI: 10.1111/j.1365-3083.1979.tb01374.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN: 0300-9475            Impact factor:   3.487


  8 in total

1.  Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: secretion of monoclonal IgM by in vitro-induced plasmablasts.

Authors:  A C Bloem; C O van Hooff; E J Bast; R E Ballieux
Journal:  Clin Exp Immunol       Date:  1984-03       Impact factor: 4.330

2.  Mitogen-stimulated immunoglobulin production by chronic lymphocytic leukaemic lymphocytes.

Authors:  A P Johnstone; J C Jensenius; R E Millard; L Hudson
Journal:  Clin Exp Immunol       Date:  1982-03       Impact factor: 4.330

3.  Interaction of Epstein-Barr virus with leukaemic B cells in vitro. I. Abortive infection and rare cell line establishment from chronic lymphocytic leukaemic cells.

Authors:  A B Rickinson; S Finerty; M A Epstein
Journal:  Clin Exp Immunol       Date:  1982-11       Impact factor: 4.330

4.  Mitogenic stimulation of malignant B cells. Chronic lymphocytic leukaemia: relationship between stimulation and surface phenotype.

Authors:  A C Bloem; E J Bast; F H Gmelig Meyling; G C DeGast; R E Ballieux
Journal:  Clin Exp Immunol       Date:  1982-11       Impact factor: 4.330

5.  Mitogen-induced maturation of chronic lymphocytic leukemia B lymphocytes.

Authors:  P Guglielmi; J L Preud'homme; R Ciorbaru-Barot; M Seligmann
Journal:  J Clin Immunol       Date:  1982-07       Impact factor: 8.317

6.  Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia.

Authors:  Z M Sthoeger; M Wakai; D B Tse; V P Vinciguerra; S L Allen; D R Budman; S M Lichtman; P Schulman; L R Weiselberg; N Chiorazzi
Journal:  J Exp Med       Date:  1989-01-01       Impact factor: 14.307

Review 7.  Chronic Lymphocytic Leukemia B-Cell Normal Cellular Counterpart: Clues From a Functional Perspective.

Authors:  Walaa Darwiche; Brigitte Gubler; Jean-Pierre Marolleau; Hussein Ghamlouch
Journal:  Front Immunol       Date:  2018-04-04       Impact factor: 7.561

8.  Interleukin 2-induced proliferation of leukemic human B cells.

Authors:  O Lantz; C Grillot-Courvalin; C Schmitt; J P Fermand; J C Brouet
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307

  8 in total

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