| Literature DB >> 23256079 |
Abstract
Near infrared (NIR) image-guided surgery holds great promise for improved surgical outcomes. A number of NIR image-guided surgical systems are currently in preclinical and clinical development with a few approved for limited clinical use. In order to wield the full power of NIR image-guided surgery, clinically available tissue and disease specific NIR fluorophores with high signal to background ratio are necessary. In the current review, the status of NIR image-guided surgery is discussed along with the desired chemical and biological properties of NIR fluorophores. Lastly, tissue and disease targeting strategies for NIR fluorophores are reviewed.Keywords: Near infrared (NIR); image-guided surgery
Year: 2012 PMID: 23256079 PMCID: PMC3496513 DOI: 10.3978/j.issn.2223-4292.2012.09.04
Source DB: PubMed Journal: Quant Imaging Med Surg ISSN: 2223-4306