Literature DB >> 23249392

Stereoselective synthesis of the disaccharide unit of incednine.

Jason R Abbott1, William R Roush.   

Abstract

A stereoselective synthesis of a fully protected version of the disaccharide unit (2) of incednine (1) is described. The synthesis of 2 proceeds in 4.7% overall yield from commercially available allyl α-d-galactopyranoside over the longest linear sequence.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 23249392      PMCID： PMC3537911          DOI： 10.1021/ol303093z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  12 in total

1.  Total synthesis of (-)-spinosyn A.

Authors:  Dustin J Mergott; Scott A Frank; William R Roush
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-01       Impact factor: 11.205

2.  Efficient and stereoselective synthesis of the disaccharide fragment of incednine.

Authors:  Takashi Ohtani; Shohei Sakai; Akira Takada; Daisuke Takahashi; Kazunobu Toshima
Journal:  Org Lett       Date:  2011-10-25       Impact factor: 6.005

Review 3.  The Bcl-2 apoptotic switch in cancer development and therapy.

Authors:  J M Adams; S Cory
Journal:  Oncogene       Date:  2007-02-26       Impact factor: 9.867

4.  Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin.

Authors:  Yushi Futamura; Ryuichi Sawa; Yoji Umezawa; Masayuki Igarashi; Hikaru Nakamura; Kimiko Hasegawa; Mikio Yamasaki; Etsu Tashiro; Yoshikazu Takahashi; Yuzuru Akamatsu; Masaya Imoto
Journal:  J Am Chem Soc       Date:  2008-01-19       Impact factor: 15.419

5.  A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo.

Authors:  Alex R Shoemaker; Anatol Oleksijew; Joy Bauch; Barbara A Belli; Tony Borre; Milan Bruncko; Thomas Deckwirth; David J Frost; Ken Jarvis; Mary K Joseph; Kennan Marsh; William McClellan; Hugh Nellans; ShiChung Ng; Paul Nimmer; Jacqueline M O'Connor; Tilman Oltersdorf; Weiguo Qing; Wang Shen; Jason Stavropoulos; Stephen K Tahir; Baole Wang; Robert Warner; Haichao Zhang; Stephen W Fesik; Saul H Rosenberg; Steven W Elmore
Journal:  Cancer Res       Date:  2006-09-01       Impact factor: 12.701

6.  Total synthesis of incednam, the aglycon of incednine.

Authors:  Takashi Ohtani; Shinya Tsukamoto; Hiroshi Kanda; Kensuke Misawa; Yoshifumi Urakawa; Takahiro Fujimaki; Masaya Imoto; Yoshikazu Takahashi; Daisuke Takahashi; Kazunobu Toshima
Journal:  Org Lett       Date:  2010-11-05       Impact factor: 6.005

7.  Synthesis of 2-O-hexadecanoyl-1-O-hexadecyl-[alpha-Glc-6SO3 Na-(1--6) -alpha-Glc-(1--6)-alpha-Glc-(1--3)]- sn-glycerol: a proposed structure for the glyceroglucolipids of human gastric secretion and of the mucous barrier of rat-stomach antrum.

Authors:  T Ogawa; T Horisaki
Journal:  Carbohydr Res       Date:  1983-11-11       Impact factor: 2.104

8.  A stereochemical surprise at the late stage of the synthesis of fully N-differentiated heparin oligosaccharides containing amino, acetamido, and N-sulfonate groups.

Authors:  Gregory J S Lohman; Peter H Seeberger
Journal:  J Org Chem       Date:  2004-06-11       Impact factor: 4.354

Review 9.  Mechanisms of apoptosis avoidance in cancer.

Authors:  J C Reed
Journal:  Curr Opin Oncol       Date:  1999-01       Impact factor: 3.645

10.  Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications.

Authors:  Hiroki Kobayashi; Hiroko Harada; Masaomi Nakamura; Yushi Futamura; Akihiro Ito; Minoru Yoshida; Shun-Ichiro Iemura; Kazuo Shin-Ya; Takayuki Doi; Takashi Takahashi; Tohru Natsume; Masaya Imoto; Yasubumi Sakakibara
Journal:  BMC Chem Biol       Date:  2012-04-05
View more
  1 in total

1.  From a decomposition product to an efficient and versatile catalyst: the [Ru(η5-indenyl)(PPh3)2Cl] story.

Authors:  Simone Manzini; José A Fernández-Salas; Steven P Nolan
Journal:  Acc Chem Res       Date:  2014-09-29       Impact factor: 22.384
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.