| Literature DB >> 23244171 |
Abstract
Clinical research in chronic obstructive pulmonary disease (COPD) has been hampered by the lack of validated blood biomarkers. The ideal COPD biomarker would have the following characteristics: (1) it would be a lung specific protein that could be assayed in blood; (2) it would change with disease severity or during exacerbations; (3) it would be specific for COPD; and would be responsive to change with effective treatments. One such candidate is the lung specific protein surfactant protein D (SP-D). In this review, we discuss the evidence supporting SP-D as a COPD biomarker.Entities:
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Year: 2012 PMID: 23244171 DOI: 10.3109/15412555.2012.736317
Source DB: PubMed Journal: COPD ISSN: 1541-2563 Impact factor: 2.409