Literature DB >> 23243045

Hypothermia in trauma.

Samuel Edwin Moffatt1.   

Abstract

Hypovolaemic shock that results through traumatically inflicted haemorrhage can have disastrous consequences for the victim. Initially the body can compensate for lost circulating volume, but as haemorrhage continues compensatory mechanisms fail and the patient's condition worsens significantly. Hypovolaemia results in the lethal triad, a combination of hypothermia, acidosis and coagulopathy, three factors that are interlinked and serve to worsen each other. The lethal triad is a form of vicious cycle, which unless broken will result in death. This report will focus on the role of hypothermia (a third of the lethal triad) in trauma, examining literature to assess how prehospital temperature control can impact on the trauma patient. Spontaneous hypothermia following trauma has severely deleterious consequences for the trauma victim; however, both active warming of patients and clinically induced hypothermia can produce particularly positive results and improve patient outcome. Possible coagulopathic side effects of clinically induced hypothermia may be corrected with topical haemostatic agents, with the benefits of an extended golden hour given by clinically induced hypothermia far outweighing these risks. Active warming of patients, to prevent spontaneous trauma induced hypothermia, is currently the only viable method currently available to improve patient outcome. This method is easy to implement requiring simple protocols and contributes significantly to interrupting the lethal triad. However, the future of trauma care appears to lie with clinically induced therapeutic hypothermia. This new treatment provides optimism that in the future the number of deaths resulting from catastrophic haemorrhaging may be significantly lessened.

Entities:  

Keywords:  Hypothermia; Military; Pre-Hospital; Trauma

Mesh:

Year:  2012        PMID: 23243045     DOI: 10.1136/emermed-2012-201883

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  8 in total

1.  Is there an association between body temperature and serum lactate levels in hip fracture patients?

Authors:  F Murtuza; A J Farrier; M Venkatesan; R Smith; A Khan; C E Uzoigwe; G Chami
Journal:  Ann R Coll Surg Engl       Date:  2015-08-14       Impact factor: 1.891

Review 2.  Hypothermia in Trauma.

Authors:  Michiel J van Veelen; Monika Brodmann Maeder
Journal:  Int J Environ Res Public Health       Date:  2021-08-18       Impact factor: 3.390

3.  5'-adenosine monophosphate-induced hypothermia attenuates brain ischemia/reperfusion injury in a rat model by inhibiting the inflammatory response.

Authors:  Yi-Feng Miao; Hui Wu; Shao-Feng Yang; Jiong Dai; Yong-Ming Qiu; Zhen-Yi Tao; Xiao-Hua Zhang
Journal:  Mediators Inflamm       Date:  2015-03-22       Impact factor: 4.711

4.  Measurements of rates of cooling of a manikin insulated with different mountain rescue casualty bags.

Authors:  Christopher Press; Christopher Duffy; Jonathan Williams; Ben Cooper; Neil Chapman
Journal:  Extrem Physiol Med       Date:  2017-04-20

5.  How do external factors contribute to the hypocoagulative state in trauma-induced coagulopathy? - In vitro analysis of the lethal triad in trauma.

Authors:  Michael Caspers; Nadine Schäfer; Matthias Fröhlich; Ursula Bauerfeind; Bertil Bouillon; Manuel Mutschler; Marc Maegele
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2018-08-15       Impact factor: 2.953

6.  Induced by infection? A case of acute myocardial infarction with hypothermia.

Authors:  Liang Li; Shudong Xia; Chao Feng
Journal:  J Int Med Res       Date:  2019-07-17       Impact factor: 1.671

7.  Risk factors for complications and in-hospital mortality: An analysis of 19,834 open pelvic ring fractures.

Authors:  Nicholas Frane; Cesar Iturriaga; Christine Bub; Peter Regala; Gus Katsigiorgis; Michael Linn
Journal:  J Clin Orthop Trauma       Date:  2020-08-25

8.  Long-Term Effects of Induced Hypothermia on Local and Systemic Inflammation - Results from a Porcine Long-Term Trauma Model.

Authors:  K Horst; D Eschbach; R Pfeifer; B Relja; M Sassen; T Steinfeldt; H Wulf; N Vogt; M Frink; S Ruchholtz; H C Pape; F Hildebrand
Journal:  PLoS One       Date:  2016-05-04       Impact factor: 3.240

  8 in total

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