PURPOSE: This study aims to evaluate the utility of a new technology, Lidocaine 5 % patch (L5%P), for providing analgesia without other sensory deficit in cancer patients with focal neuropathic pain (NP) related or not with cancer. METHODS: During the period February 2011 to July 2011, 83 patients were seen for the first time in our department and L5%P were prescribed to 15 of those patients (18.07 %). Information recorded in relation to the L5%P included the following: (a) Nature of NP, (b) medications tested, (c) drug combinations, (d) L5%P therapy duration, (e) efficacy, and (f) undesirable effects. RESULTS: Forty percent of the patients (n = 6) in our series had NP related to their cancer and 60 % (n = 9), chronic NP not related to their cancer diagnosis, but all referred to our Radiotherapy and Oncology Department for radiotherapy. The analgesic effect of the L5%P was potent in eight cases (53.33 %) and partial in four cases (26.66 %). This represents 79.99 % efficacy in selected patients. There were no serious adverse events reported in any of the patients. CONCLUSION: The results indicate that there are patients with NP within a cancer setting who are suitable for treatment and successfully managed with topical L5%P, alone or in combination with other drugs.
PURPOSE: This study aims to evaluate the utility of a new technology, Lidocaine 5 % patch (L5%P), for providing analgesia without other sensory deficit in cancerpatients with focal neuropathic pain (NP) related or not with cancer. METHODS: During the period February 2011 to July 2011, 83 patients were seen for the first time in our department and L5%P were prescribed to 15 of those patients (18.07 %). Information recorded in relation to the L5%P included the following: (a) Nature of NP, (b) medications tested, (c) drug combinations, (d) L5%P therapy duration, (e) efficacy, and (f) undesirable effects. RESULTS: Forty percent of the patients (n = 6) in our series had NP related to their cancer and 60 % (n = 9), chronic NP not related to their cancer diagnosis, but all referred to our Radiotherapy and Oncology Department for radiotherapy. The analgesic effect of the L5%P was potent in eight cases (53.33 %) and partial in four cases (26.66 %). This represents 79.99 % efficacy in selected patients. There were no serious adverse events reported in any of the patients. CONCLUSION: The results indicate that there are patients with NP within a cancer setting who are suitable for treatment and successfully managed with topical L5%P, alone or in combination with other drugs.
Authors: Andrea L Cheville; Jeff A Sloan; Donald W Northfelt; Anand P Jillella; Gilbert Y Wong; James D Bearden Iii; Heshan Liu; Paul L Schaefer; Benjamin T Marchello; Bradley J Christensen; Charles L Loprinzi Journal: Support Care Cancer Date: 2009-01-13 Impact factor: 3.603
Authors: Concepcion Perez; Rafael Galvez; Silvia Huelbes; Joaquin Insausti; Didier Bouhassira; Silvia Diaz; Javier Rejas Journal: Health Qual Life Outcomes Date: 2007-12-04 Impact factor: 3.186
Authors: John F Peppin; Phillip J Albrecht; Charles Argoff; Burkhard Gustorff; Marco Pappagallo; Frank L Rice; Mark S Wallace Journal: Pain Ther Date: 2015-01-29