Literature DB >> 23242080

An unusual suspect causing behavioural problems and pituitary failure in a child.

Adam Charles Heathcote1, Justin Conrad Rosen Wormald, Richard Stocks.   

Abstract

A 9-year-old boy presented with feeding and behavioural problems and was diagnosed with Autistic Spectrum Disorder and Attention Deficit Hyperactivity Disorder. By age 11 he was becoming increasingly disinhibited and was refusing almost all oral food intake. Believing the cause to be psychogenic, he was placed in an inpatient eating disorder facility. After 3 days of continuous vomiting and minimal intake, he was admitted back to hospital for further investigations. A hypovolaemic hypernatraemia prompted an MRI brain scan, revealing several tumour masses with suprasellar and pituitary involvement. Histological investigation revealed primary, non-malignant germ-cell tumours. The tumours were treated with craniopharyngeal radiotherapy and permanent pituitary hormone replacement.

Entities:  

Mesh:

Year:  2012        PMID: 23242080      PMCID: PMC4544023          DOI: 10.1136/bcr-2012-006870

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Laboratory reference values.

Authors:  Alexander Kratz; Maryjane Ferraro; Patrick M Sluss; Kent B Lewandrowski
Journal:  N Engl J Med       Date:  2004-10-07       Impact factor: 91.245

2.  Aarskog syndrome.

Authors:  M E Porteous; D R Goudie
Journal:  J Med Genet       Date:  1991-01       Impact factor: 6.318

Review 3.  Diagnosis and treatment of hypopituitarism: an update.

Authors:  M O van Aken; S W J Lamberts
Journal:  Pituitary       Date:  2005       Impact factor: 4.107

4.  Lymphocytic hypophysitis with central diabetes insipidus and subsequent hypopituitarism masking a suprasellar germinoma in a 13-year-old girl.

Authors:  Yoko Mikami-Terao; Masaharu Akiyama; Takaaki Yanagisawa; Junko Takahashi-Fujigasaki; Kentaro Yokoi; Kohei Fukuoka; Mio Sakuma; Ichiro Miyata; Kohji Fujisawa; Shizuo Oi; Yoshikatsu Eto
Journal:  Childs Nerv Syst       Date:  2006-03-25       Impact factor: 1.475

5.  Autistic spectrum disorders.

Authors:  L Wing
Journal:  BMJ       Date:  1996-02-10

6.  Recognising and diagnosing autism in children and young people: summary of NICE guidance.

Authors:  Gillian Baird; Hannah Rose Douglas; M Stephen Murphy
Journal:  BMJ       Date:  2011-10-21

7.  Why are brain tumours still being missed?

Authors:  J Edgeworth; P Bullock; A Bailey; A Gallagher; M Crouchman
Journal:  Arch Dis Child       Date:  1996-02       Impact factor: 3.791

8.  Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP).

Authors:  Gillian Baird; Emily Simonoff; Andrew Pickles; Susie Chandler; Tom Loucas; David Meldrum; Tony Charman
Journal:  Lancet       Date:  2006-07-15       Impact factor: 79.321

9.  Hydrocortisone dose and postoperative diabetes insipidus in patients undergoing transsphenoidal pituitary surgery: a prospective randomized controlled study.

Authors:  S Rajaratnam; M S Seshadri; M J Chandy; V Rajshekhar
Journal:  Br J Neurosurg       Date:  2003-10       Impact factor: 1.596

10.  Epidemiological survey of central nervous system germ cell tumors in Canadian children.

Authors:  D Keene; D Johnston; D Strother; C Fryer; A S Carret; B Crooks; D Eisenstat; A Moghrabi; B Wilson; J Brossard; C Mpofu; I Odame; S Zelcer; M Silva; Y Samson; J Hand; E Bouffet
Journal:  J Neurooncol       Date:  2006-11-22       Impact factor: 4.506

View more
  1 in total

1.  Psychiatric manifestations as initial presentation for pediatric CNS germ cell tumors, a case series.

Authors:  F Malbari; T R Gershon; J H Garvin; J C Allen; Y Khakoo; A S Levy; I J Dunkel
Journal:  Childs Nerv Syst       Date:  2016-06-16       Impact factor: 1.475

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.