Literature DB >> 23239292

Reduction in obesity-related comorbidities: is gastric bypass better than sleeve gastrectomy?

Niu Zhang1, Anthony Maffei, Thomas Cerabona, Anil Pahuja, Juan Omana, Ashutosh Kaul.   

Abstract

BACKGROUND: Bariatric surgery is currently the most effective treatment for morbid obesity. It provides not only substantial weight loss, but also resolution of obesity-related comorbidities. Laparoscopic sleeve gastrectomy (LSG) has rapidly been gaining in popularity. However, there are limited data on the reduction of obesity-related comorbidities for LSG compared to laparoscopic Roux-en-Y gastric bypass (LRYGB). The aim of this study was to assess the effectiveness of laparoscopic LSG versus LRYGB for the treatment of obesity-related comorbidities.
METHODS: A total of 558 patients who underwent either LSG or LRYGB for morbid obesity at the Westchester Medical Center between April 2008 and September 2010 were included. Data were collected prospectively into a computerized database and reviewed for this study. Fisher's exact test analyses compared 30-day, 6-month, and 1-year outcomes of obesity-related comorbidities.
RESULTS: A total of 558 patients were included in the analysis of obesity-related comorbidity resolution; 200 underwent LSG and 358 underwent LRYGB. After 1 year, 86.2 % of the LSG patients had one or more comorbidities in remission compared to 83.1 % LRYGB patients (P = 0.688). With the exception of GERD (-0.09 vs. 50 %; P < 0.001), similar comorbidity remission rates were observed between LSG and LRYGB for sleep apnea (91.2 vs. 82.8 %; P = 0.338), hyperlipidemia (63 vs. 55.8 %; P = 0.633), hypertension (38.8 vs. 52.9 %; P = 0.062), diabetes (58.6 vs. 65.5 %; P = 0.638), and musculoskeletal disease (66.7 vs. 79.4 %; P = 0.472).
CONCLUSIONS: Laparoscopic sleeve gastrectomy markedly improves most obesity-related comorbidities. Compared to LRYGB, LSG may have equal in reducing sleep apnea, hyperlipidemia, hypertension, diabetes, and musculoskeletal disease. LRYGB appears to be more effective at GERD resolution than LSG.

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Year:  2012        PMID: 23239292     DOI: 10.1007/s00464-012-2595-7

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  35 in total

1.  Excess weight and sleep-disordered breathing.

Authors:  Terry Young; Paul E Peppard; Shahrad Taheri
Journal:  J Appl Physiol (1985)       Date:  2005-10

2.  Accelerated growth of bariatric surgery with the introduction of minimally invasive surgery.

Authors:  Ninh T Nguyen; Jeffrey Root; Kambiz Zainabadi; Allen Sabio; Sara Chalifoux; C Melinda Stevens; Shahrzad Mavandadi; Mario Longoria; Samuel E Wilson
Journal:  Arch Surg       Date:  2005-12

3.  Dilated upper sleeve can be associated with severe postoperative gastroesophageal dysmotility and reflux.

Authors:  Andrei Keidar; Liat Appelbaum; Chaya Schweiger; Ram Elazary; Aniceto Baltasar
Journal:  Obes Surg       Date:  2009-12-01       Impact factor: 4.129

Review 4.  Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: understanding weight loss and improvements in type 2 diabetes after bariatric surgery.

Authors:  William R Scott; Rachel L Batterham
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-04-06       Impact factor: 3.619

Review 5.  Changes in neurohormonal gut peptides following bariatric surgery.

Authors:  C N Ochner; C Gibson; M Shanik; V Goel; A Geliebter
Journal:  Int J Obes (Lond)       Date:  2010-07-13       Impact factor: 5.095

6.  Laparoscopic sleeve gastrectomy as a stand-alone procedure for morbid obesity: report of 1,000 cases and 3-year follow-up.

Authors:  Camilo Boza; José Salinas; Napoleón Salgado; Gustavo Pérez; Alejandro Raddatz; Ricardo Funke; Fernando Pimentel; Luis Ibáñez
Journal:  Obes Surg       Date:  2012-06       Impact factor: 4.129

7.  Laparoscopic sleeve gastrectomy as a single-stage procedure for the treatment of morbid obesity and the resulting quality of life, resolution of comorbidities, food tolerance, and 6-year weight loss.

Authors:  Mathieu D'Hondt; Sofie Vanneste; Hans Pottel; Dirk Devriendt; Frank Van Rooy; Franky Vansteenkiste
Journal:  Surg Endosc       Date:  2011-02-27       Impact factor: 4.584

8.  Laparoscopic sleeve gastrectomy for obesity: can it be considered a definitive procedure?

Authors:  Ajay Chopra; Edward Chao; Yana Etkin; Lynn Merklinger; Jayne Lieb; Harry Delany
Journal:  Surg Endosc       Date:  2011-12-17       Impact factor: 4.584

9.  Manometric changes of the lower esophageal sphincter after sleeve gastrectomy in obese patients.

Authors:  Italo Braghetto; Enrique Lanzarini; Owen Korn; Héctor Valladares; Juan Carlos Molina; Ana Henriquez
Journal:  Obes Surg       Date:  2009-12-15       Impact factor: 4.129

10.  Percentage of excess BMI lost correlates better with improvement of metabolic syndrome after Roux-en-Y gastric bypass in morbidly obese subjects: anthropometric indexes and gastric bypass.

Authors:  Marçal Rossi; Ary Serpa Neto; Felipe Martin Bianco Rossi; Rodrigo Dal Moro Amarante; Geraldo Chaves Alcântara; Renato Barretto Ferreira da Silva; Paulo Fernando Regina
Journal:  Surg Obes Relat Dis       Date:  2008-08-13       Impact factor: 4.734

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  37 in total

1.  A Comparison of the Bariatric Procedures that Are Performed in the Treatment of Super Morbid Obesity.

Authors:  Kohei Uno; Yosuke Seki; Kazunori Kasama; Kotaro Wakamatsu; Akiko Umezawa; Katsuhiko Yanaga; Yoshimochi Kurokawa
Journal:  Obes Surg       Date:  2017-10       Impact factor: 4.129

2.  Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass. Data from IFSO-European Chapter Center of Excellence Program.

Authors:  John Melissas; Konstantinos Stavroulakis; Vassilis Tzikoulis; Angeliki Peristeri; John A Papadakis; Abdolreza Pazouki; Alireza Khalaj; Ali Kabir
Journal:  Obes Surg       Date:  2017-04       Impact factor: 4.129

3.  Sleeve Gastrectomy with Ligamentum Teres Cardiopexy.

Authors:  Chih-Kun Huang; Michelle Bernadette C Lim-Loo; Emmanuel S Astudillo; Ming Chen Hsin
Journal:  Obes Surg       Date:  2018-08       Impact factor: 4.129

Review 4.  The impact of obesity surgery on musculoskeletal disease.

Authors:  Ussamah El-Khani; Ahmed Ahmed; Sherif Hakky; Jean Nehme; Jonathan Cousins; Harvinder Chahal; Sanjay Purkayastha
Journal:  Obes Surg       Date:  2014-12       Impact factor: 4.129

5.  A meta-analysis of 2-year effect after surgery: laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy for morbid obesity and diabetes mellitus.

Authors:  Chengda Zhang; Yuan Yuan; Cuiqiong Qiu; Weidong Zhang
Journal:  Obes Surg       Date:  2014-09       Impact factor: 4.129

Review 6.  Sleep Duration and Quality: Impact on Lifestyle Behaviors and Cardiometabolic Health: A Scientific Statement From the American Heart Association.

Authors:  Marie-Pierre St-Onge; Michael A Grandner; Devin Brown; Molly B Conroy; Girardin Jean-Louis; Michael Coons; Deepak L Bhatt
Journal:  Circulation       Date:  2016-09-19       Impact factor: 29.690

7.  Resolution of Symptomatic Obstructive Sleep Apnea Not Impacted by Preoperative Body Mass Index, Choice of Operation Between Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Surgery, or Severity.

Authors:  Kamyar Hariri; Subhash U Kini; Daniel M Herron; Gustavo Fernandez-Ranvier
Journal:  Obes Surg       Date:  2018-05       Impact factor: 4.129

Review 8.  Gastroesophageal Reflux After Sleeve Gastrectomy.

Authors:  Francisco A Guzman-Pruneda; Stacy A Brethauer
Journal:  J Gastrointest Surg       Date:  2020-09-15       Impact factor: 3.452

9.  Pancreatic Head Resection Following Roux-en-Y Gastric Bypass: Operative Considerations and Outcomes.

Authors:  M T Trudeau; L Maggino; B L Ecker; C M Vollmer
Journal:  J Gastrointest Surg       Date:  2019-09-04       Impact factor: 3.452

10.  Remission of Type 2 Diabetes and Sleeve Gastrectomy in Morbid Obesity: a Comparative Systematic Review and Meta-analysis.

Authors:  Ferdous Madadi; Rami Jawad; Ismail Mousati; Philip Plaeke; Guy Hubens
Journal:  Obes Surg       Date:  2019-12       Impact factor: 4.129

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