Literature DB >> 23232554

Evaluation of lymph node metastasis in patients with gastric cancer: a comparison of the directionality of lymph node metastasis and the total number of metastatic lymph nodes.

Maki Kitagawa1, Daisuke Ichikawa, Shuhei Komatsu, Kazuma Okamoto, Atsushi Shiozaki, Hitoshi Fujiwara, Yasutoshi Murayama, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi, Toshiya Ochiai, Yukihito Kokuba, Teruhisa Sonoyama, Eigo Otsuji.   

Abstract

PURPOSE: The clinical impact of the directionality of lymph node (LN) metastasis was assessed in comparison with the staging by the Japanese Classification of Gastric Carcinoma (JCGC), a numerical LN staging system.
METHODS: Two hundred forty-one gastric cancer patients who were diagnosed pathologically to have LN metastasis, and 54 patients who underwent preoperative multidetector-row computed tomography (MDCT) with an image thickness of 1 mm were classified into three groups (unidirectional [Uni-], bidirectional [Bi-], and tridirectional [Tri-] groups) depending on the directionality of their LN metastasis.
RESULTS: The prognosis of the Uni-group was better than that of the Bi- or the Tri-group when assessed on the basis of the pathological findings of metastatic LN and also the preoperative MDCT findings. The exact preoperative evaluation was 70.2 % for the directionality system and 61.7 % for the JCGC system, respectively. The stages were less frequently underestimated by the directionality system than the JCGC system (P < 0.02, 19.1 vs. 34.0 %), and the staging could be more precisely performed by both systems in combination.
CONCLUSIONS: More precise preoperative evaluation of disease stage could be obtained by the directionality system and the JCGC system in combination.

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Year:  2012        PMID: 23232554     DOI: 10.1007/s00595-012-0454-8

Source DB:  PubMed          Journal:  Surg Today        ISSN: 0941-1291            Impact factor:   2.549


  18 in total

1.  The directionality of lymphatic spreading as a prognostic factor in gastric cancer: uni- or multidirectional lymphatic metastases.

Authors:  Maki Kitagawa; Daisuke Ichikawa; Shuhei Komatsu; Kazuma Okamoto; Atsushi Shiozaki; Hitoshi Fujiwara; Yoshiaki Kuriu; Hisashi Ikoma; Masayoshi Nakanishi; Toshiya Ochiai; Yukihito Kokuba; Eigo Otsuji
Journal:  Hepatogastroenterology       Date:  2011 Nov-Dec

Review 2.  Imaging in assessing lymph node status in gastric cancer.

Authors:  Robert Michael Kwee; Thomas Christian Kwee
Journal:  Gastric Cancer       Date:  2009-04-24       Impact factor: 7.370

3.  Detection of sentinel node by fluorescence and infrared ray imaging system in gastric cancer.

Authors:  Naoto Takahashi; Hiroshi Nimura; Tetsuji Fujita; Norio Mitsumori; Hideyuki Kashiwagi; Katsuhiko Yanaga
Journal:  Ann Surg Oncol       Date:  2009-04-02       Impact factor: 5.344

4.  A study of the assessment of axillary lymph nodes before surgery for breast cancer using multidetector-row computed tomography.

Authors:  Yuya Nasu; Hiroyuki Shikishima; Yuji Miyasaka; Yoshihiro Nakakubo; Kazuomi Ichinokawa; Toshifumi Kaneko
Journal:  Surg Today       Date:  2010-11-03       Impact factor: 2.549

5.  Japanese classification of gastric carcinoma: 3rd English edition.

Authors: 
Journal:  Gastric Cancer       Date:  2011-06       Impact factor: 7.370

6.  Spiral computed tomography and operative staging of gastric carcinoma: a comparison with histopathological staging.

Authors:  J Davies; A G Chalmers; H M Sue-Ling; J May; G V Miller; I G Martin; D Johnston
Journal:  Gut       Date:  1997-09       Impact factor: 23.059

7.  Prognostic value of preoperative clinical staging assessed by computed tomography in resectable gastric cancer patients: a viewpoint in the era of preoperative treatment.

Authors:  Sook Ryun Park; Min Ju Kim; Keun Won Ryu; Jun Ho Lee; Jong Seok Lee; Byung-Ho Nam; Il Ju Choi; Young-Woo Kim
Journal:  Ann Surg       Date:  2010-03       Impact factor: 12.969

8.  Neoadjuvant chemotherapy followed by salvage surgery: effect on survival of patients with primary noncurative gastric cancer.

Authors:  Masahiko Yano; Hitoshi Shiozaki; Masatoshi Inoue; Shigeyuki Tamura; Yuichiro Doki; Takushi Yasuda; Yoshiyuki Fujiwara; Toshimasa Tsujinaka; Morito Monden
Journal:  World J Surg       Date:  2002-06-24       Impact factor: 3.352

9.  Phase II study of neoadjuvant chemotherapy and extended surgery for locally advanced gastric cancer.

Authors:  T Yoshikawa; M Sasako; S Yamamoto; T Sano; H Imamura; K Fujitani; H Oshita; S Ito; Y Kawashima; N Fukushima
Journal:  Br J Surg       Date:  2009-09       Impact factor: 6.939

10.  Prognostic value of lymph node staging in gastric cancer.

Authors:  Daisuke Ichikawa; Hideaki Kurioka; Yasuo Ueshima; Koichi Shirono; Keitaro Kan; Yasuhiro Shioaki; Chol Joo Lee; Takashi Hamashima; Eiichi Deguchi; Eito Ikeda; Fumitaka Mutoh; Hisakazu Yamagishi
Journal:  Hepatogastroenterology       Date:  2003 Jan-Feb
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  2 in total

1.  Prognostic significance of metastatic lymph node number, ratio and station in gastric neuroendocrine carcinoma.

Authors:  Xiaolong Tang; Yingtai Chen; Lanwei Guo; Jianwei Zhang; Chengfeng Wang
Journal:  J Gastrointest Surg       Date:  2014-11-14       Impact factor: 3.452

2.  The Significant Influence of the Neuroendocrine Component on the Survival of Patients with Gastric Carcinoma Characterized by Coexisting Exocrine and Neuroendocrine Components.

Authors:  Hu Ren; Su-Sheng Shi; Nian-Chang Wang; Xing Wang; Ying-Tai Chen; Dong-Bing Zhao
Journal:  J Oncol       Date:  2019-03-12       Impact factor: 4.375

  2 in total

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