Literature DB >> 23232184

The untapped potential of Gallium 68-PET: the next wave of ⁶⁸Ga-agents.

Daniel L Smith1, Wouter A P Breeman, Jennifer Sims-Mourtada.   

Abstract

(68)Gallium-PET ((68)Ga-PET) agents have significant clinical promise. The radionuclide can be produced from a (68)Ge/(68)Ga generator on site and is a convenient alternative to cyclotron-based PET isotopes. The short half-life of (68)Ga permits imaging applications with sufficient radioactivity while maintaining patient dose to an acceptable level. Furthermore, due to superior resolution, (68)Ga-PET agents have the ability to replace current SPECT agents in many applications. This article outlines the upcoming agents and challenges faced during the translational development of (68)Ga agents.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 23232184     DOI： 10.1016/j.apradiso.2012.10.014

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  14 in total

1.  Cyclotron production of (68)Ga via the (68)Zn(p,n)(68)Ga reaction in aqueous solution.

Authors:  Mukesh K Pandey; John F Byrne; Huailei Jiang; Alan B Packard; Timothy R DeGrado
Journal:  Am J Nucl Med Mol Imaging       Date:  2014-06-07

Review 2.  68Ga-DOTA and analogs: Current status and future perspectives.

Authors:  Krzysztof Kilian
Journal:  Rep Pract Oncol Radiother       Date:  2014-05-19

3.  Preliminary PET/CT Imaging with Somatostatin Analogs [68Ga]DOTAGA-TATE and [68Ga]DOTAGA-TOC.

Authors:  Drishty Satpati; Ajit Shinto; K K Kamaleshwaran; Haladhar Dev Sarma; Ashutosh Dash
Journal:  Mol Imaging Biol       Date:  2017-12       Impact factor: 3.488

4.  68Ga-THP-PSMA: A PET Imaging Agent for Prostate Cancer Offering Rapid, Room-Temperature, 1-Step Kit-Based Radiolabeling.

Authors:  Jennifer D Young; Vincenzo Abbate; Cinzia Imberti; Levente K Meszaros; Michelle T Ma; Samantha Y A Terry; Robert C Hider; Greg E Mullen; Philip J Blower
Journal:  J Nucl Med       Date:  2017-04-13       Impact factor: 10.057

5.  Radiosynthesis of [18F]SiFAlin-TATE for clinical neuroendocrine tumor positron emission tomography.

Authors:  Simon Lindner; Carmen Wängler; Björn Wängler; Ralf Schirrmacher; Justin J Bailey; Klaus Jurkschat; Peter Bartenstein
Journal:  Nat Protoc       Date:  2020-11-23       Impact factor: 13.491

6.  DATATOC: a novel conjugate for kit-type 68Ga labelling of TOC at ambient temperature.

Authors:  Johanna Seemann; Bradley Waldron; David Parker; Frank Roesch
Journal:  EJNMMI Radiopharm Chem       Date:  2016-03-21

7.  Otto: a 4.04 GBq (109 mCi) 68Ge/68Ga generator, first of its kind - extended quality control and performance evaluation in the clinical production of [68Ga]Ga-PSMA-11.

Authors:  Nicole N Waterhouse; Alejandro Amor-Coarasa; Anastasia Nikolopoulou; John W Babich
Journal:  EJNMMI Radiopharm Chem       Date:  2020-02-03

8.  Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target.

Authors:  Melissa E Rodnick; Carina Sollert; Daniela Stark; Mara Clark; Andrew Katsifis; Brian G Hockley; D Christian Parr; Jens Frigell; Bradford D Henderson; Monica Abghari-Gerst; Morand R Piert; Michael J Fulham; Stefan Eberl; Katherine Gagnon; Peter J H Scott
Journal:  EJNMMI Radiopharm Chem       Date:  2020-11-12

9.  Targeting MT1-MMP as an ImmunoPET-Based Strategy for Imaging Gliomas.

Authors:  A G de Lucas; A J Schuhmacher; M Oteo; E Romero; J A Cámara; A de Martino; A G Arroyo; M Á Morcillo; M Squatrito; J L Martinez-Torrecuadrada; F Mulero
Journal:  PLoS One       Date:  2016-07-27       Impact factor: 3.240

10.  In Vivo Imaging of Experimental Melanoma Tumors using the Novel Radiotracer 68Ga-NODAGA-Procainamide (PCA).

Authors:  István Kertész; András Vida; Gábor Nagy; Miklós Emri; Antal Farkas; Adrienn Kis; János Angyal; Noémi Dénes; Judit P Szabó; Tünde Kovács; Péter Bai; György Trencsényi
Journal:  J Cancer       Date:  2017-02-25       Impact factor: 4.207
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