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Literature DB >> 23229449

Clinical relevance of bone marrow lesions in OA.

Abstract

Advances in imaging have improved our understanding of the relationship between pathology and the structural changes to joints affected by osteoarthritis. New research indicates that subchondral bone marrow lesions might represent a potential imaging biomarker to quantify such structural changes.

Entities: Disease

Mesh：

Year: 2012 PMID： 23229449 DOI： 10.1038/nrrheum.2012.217

Source DB: PubMed Journal: Nat Rev Rheumatol ISSN： 1759-4790 Impact factor: 20.543

9 in total

1. Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis: a three-month longitudinal study.

Authors: P Garnero; C Peterfy; S Zaim; M Schoenharting
Journal: Arthritis Rheum Date: 2005-09

Review 2. Bone marrow changes in osteoarthritis.

Authors: Thomas M Link; Xiaojuan Li
Journal: Semin Musculoskelet Radiol Date: 2011-06-03 Impact factor: 1.777

3. Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging.

Authors: Yuqing Zhang; Michael Nevitt; Jingbo Niu; Cora Lewis; James Torner; Ali Guermazi; Frank Roemer; Charles McCulloch; David T Felson
Journal: Arthritis Rheum Date: 2011-03

Review 4. Definition of osteoarthritis on MRI: results of a Delphi exercise.

Authors: D J Hunter; N Arden; P G Conaghan; F Eckstein; G Gold; A Grainger; A Guermazi; W Harvey; G Jones; M P Hellio Le Graverand; J D Laredo; G Lo; E Losina; T J Mosher; F Roemer; W Zhang
Journal: Osteoarthritis Cartilage Date: 2011-05-12 Impact factor: 6.576

Review 5. A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials.

Authors: David J Hunter; Elena Losina; Ali Guermazi; Deb Burstein; Marissa N Lassere; Virginia Kraus
Journal: Curr Drug Targets Date: 2010-05 Impact factor: 3.465

6. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial.

Authors: Laura Louise Laslett; Dawn A Doré; Stephen J Quinn; Philippa Boon; Emma Ryan; Tania Maree Winzenberg; Graeme Jones
Journal: Ann Rheum Dis Date: 2012-02-21 Impact factor: 19.103

7. Bone marrow lesions are associated with altered trabecular morphometry.

Authors: J B Driban; A Tassinari; G H Lo; L L Price; E Schneider; J A Lynch; C B Eaton; T E McAlindon
Journal: Osteoarthritis Cartilage Date: 2012-08-30 Impact factor: 6.576

Review 8. Why radiography should no longer be considered a surrogate outcome measure for longitudinal assessment of cartilage in knee osteoarthritis.

Authors: Ali Guermazi; Frank W Roemer; Deborah Burstein; Daichi Hayashi
Journal: Arthritis Res Ther Date: 2011-11-24 Impact factor: 5.156

9. Bone marrow lesions in knee osteoarthritis change in 6-12 weeks.

Authors: D T Felson; M J Parkes; E J Marjanovic; M Callaghan; A Gait; T Cootes; M Lunt; J Oldham; C E Hutchinson
Journal: Osteoarthritis Cartilage Date: 2012-09-01 Impact factor: 6.576

9 in total

1. Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain.

Authors: Shouan Zhu; Jianxi Zhu; Gehua Zhen; Yihe Hu; Senbo An; Yusheng Li; Qin Zheng; Zhiyong Chen; Ya Yang; Mei Wan; Richard Leroy Skolasky; Yong Cao; Tianding Wu; Bo Gao; Mi Yang; Manman Gao; Julia Kuliwaba; Shuangfei Ni; Lei Wang; Chuanlong Wu; David Findlay; Holger K Eltzschig; Hong Wei Ouyang; Janet Crane; Feng-Quan Zhou; Yun Guan; Xinzhong Dong; Xu Cao
Journal: J Clin Invest Date: 2019-02-04 Impact factor: 14.808

Clinical relevance of bone marrow lesions in OA.

1. Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis: a three-month longitudinal study.

Review 2. Bone marrow changes in osteoarthritis.

3. Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging.

Review 4. Definition of osteoarthritis on MRI: results of a Delphi exercise.

Review 5. A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials.

6. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial.

7. Bone marrow lesions are associated with altered trabecular morphometry.

Review 8. Why radiography should no longer be considered a surrogate outcome measure for longitudinal assessment of cartilage in knee osteoarthritis.

9. Bone marrow lesions in knee osteoarthritis change in 6-12 weeks.

1. Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain.

Review 2. Clinical and translational potential of MRI evaluation in knee osteoarthritis.

3. Osteoarthritis: Osteoporotic OA: a reasonable target for bone-acting agents.

Review 4. Mechanisms of bone pain: Progress in research from bench to bedside.

Review 5. Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis.

6. Knee joint pain potentially due to bone alterations in a knee osteoarthritis patient.

7. Aberrant subchondral osteoblastic metabolism modifies Na_V1.8 for osteoarthritis.

8. Parathyroid hormone attenuates osteoarthritis pain by remodeling subchondral bone in mice.

9. Peripheral nerves in the tibial subchondral bone : the role of pain and homeostasis in osteoarthritis.