Literature DB >> 2322494

The discrimination between nickel-sensitive and non-nickel-sensitive subjects by an in vitro lymphocyte transformation test.

K M Everness1, D J Gawkrodger, P A Botham, J A Hunter.   

Abstract

A lymphocyte transformation test (LTT) was able to distinguish between nickel-sensitive subjects and non-nickel-sensitive controls. Sixty-one out of 66 (92%) nickel-sensitive subjects had positive stimulation indices in 6- and/or 7-day assays using 5 micrograms/ml of nickel sulphate, whereas none of the 43 controls gave positive results. Stimulation indices were not enhanced by the patch testing of subjects to nickel before performing the LTT. A weak correlation was seen between the results of the LTT and the macroscopic degree of patch-test reactivity. The concentration of nickel sulphate used (5 micrograms/ml) did not have a significant non-specific mitogenic effect.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2322494     DOI： 10.1111/j.1365-2133.1990.tb08276.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  14 in total

Review 1.  Patch testing in occupational dermatology.

Authors:  D J Gawkrodger
Journal:  Occup Environ Med       Date:  2001-12       Impact factor: 4.402

2.  Cytometric and electron microscopic studies of the direct interaction of divalent nickel with intact and chemically modified HuT-78 lymphoblasts.

Authors:  G I Malinin; F J Hornicek; H K Lo; T I Malinin
Journal:  Cell Biol Toxicol       Date:  1992 Jan-Mar       Impact factor: 6.691

3.  In vitro reactivity to implant metals demonstrates a person-dependent association with both T-cell and B-cell activation.

Authors:  Nadim James Hallab; Marco Caicedo; Rachel Epstein; Kyron McAllister; Joshua J Jacobs
Journal:  J Biomed Mater Res A       Date:  2010-02       Impact factor: 4.396

4.  Asymptomatic prospective and retrospective cohorts with metal-on-metal hip arthroplasty indicate acquired lymphocyte reactivity varies with metal ion levels on a group basis.

Authors:  Nadim J Hallab; Marco Caicedo; Kyron McAllister; Anastasia Skipor; Harlan Amstutz; Joshua J Jacobs
Journal:  J Orthop Res       Date:  2012-08-31       Impact factor: 3.494

5.  Total knee arthroplasty in patients with hypersensitivity to metals.

Authors:  Massimo Innocenti; Christian Carulli; Fabrizio Matassi; Anna Maria Carossino; Maria Luisa Brandi; Roberto Civinini
Journal:  Int Orthop       Date:  2014-01-04       Impact factor: 3.075

6.  Lymphocyte transformation test reveals low prevalence of true metal hypersensitivity among pre-operative total knee arthroplasty patients.

Authors:  Tarek Boutefnouchet; Francis Vallières; Josee Delisle; Mohamed Benderdour; Julio C Fernandes
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2022-04-05       Impact factor: 4.342

Review 7.  [Tolerance induction towards nickel. From animal model to humans].

Authors:  S Artik; E Gleichmann; T Ruzicka
Journal:  Hautarzt       Date:  2004-11       Impact factor: 0.751

8.  Association of CD69 up-regulation on CD4+ Cla+ T cells versus patch test, strip patch test and clinical history in nickel sensitization.

Authors:  Heinrich Dickel; O Kuss; J Kamphowe; P Altmeyer; S Höxtermann
Journal:  Eur J Med Res       Date:  2010       Impact factor: 2.175

9.  Do Battlefield Injury-acquired Indwelling Metal Fragments Induce Metal Immunogenicity?

Authors:  Lauryn Samelko; Joseph Petfield; Kyron McAllister; Joseph Hsu; Michael Hawkinson; Joshua J Jacobs; Nadim J Hallab
Journal:  Clin Orthop Relat Res       Date:  2020-04       Impact factor: 4.755

10.  Nickel, palladium and rhodium induced IFN-gamma and IL-10 production as assessed by in vitro ELISpot-analysis in contact dermatitis patients.

Authors:  Valentina Bordignon; Francesca Palamara; Paola Cordiali-Fei; Antonella Vento; Arianna Aiello; Mauro Picardo; Fabrizio Ensoli; Antonio Cristaudo
Journal:  BMC Immunol       Date:  2008-05-15       Impact factor: 3.615
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.